2023
DOI: 10.1007/s43450-023-00371-0
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Metabolomic Profiling and Cytotoxic Activity of Launaea nudicaulis: Molecular Docking with Topoisomerases

Abstract: Launaea nudicaulis (L.) Hook. f., Asteraceae, is a wild plant growing in Egypt, used traditionally for treatment of many diseases. LC-HRMS analysis of different polarity soluble extracts allowed the annotation of fifteen compounds: three alkaloids, four flavonoids, three phenolic acids, three coumarins, one sphingolipid, and one triterpene. Chemical investigation led to isolation and identification of caffeic acid, luteolin, luteolin7-O-glucoside, lupeol, β-sitosterol, and palmitic acid. Cytotoxic evaluation f… Show more

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