Metabolomics Analysis of Cell-Free Expression Systems Using Gas Chromatography-Mass Spectrometry

Miguez, April M.; Zhang, Yan; Styczynski, Mark P.

doi:10.1007/978-1-0716-1998-8_13

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2024

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Cited by 2 publications

References 19 publications

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Cell-Free Systems in Metabolomics

Kumar,

Israr,

Mishra

et al. 2024

Advances in Metabolomics

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Cell-Free Systems in Metabolomics

Kumar,

Israr,

Mishra

et al. 2024

Advances in Metabolomics

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The Application of Metabolomics in Hyperlipidemia: Insights into Biomarker Discovery and Treatment Efficacy Assessment

Alwahsh,

Alejel,

Hasan

et al. 2024

Metabolites

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Hyperlipidemia is a lipid metabolism disorder that refers to increased levels of total triglycerides (TGs), cholesterol (TC), and low-density lipoprotein-cholesterol (LDL-C) and decreased levels of high-density lipoprotein-cholesterol (HDL-C). It is a major public health issue with increased prevalence and incidence worldwide. The ability to identify individuals at risk of this disorder before symptoms manifest will facilitate timely intervention and management to avert potential complications. This can be achieved by employing metabolomics as an early detection method for the diagnostic biomarkers of hyperlipidemia. Metabolomics is an analytical approach used to detect and quantify metabolites. This provides the ability to explain the metabolic processes involved in the development and progression of certain diseases. In recent years, interest in the use of metabolomics to identify disease biomarkers has increased, and several biomarkers have been discovered, such as docosahexaenoic acid, glycocholic acid, citric acid, betaine, and carnitine. This review discusses the primary metabolic alterations in the context of hyperlipidemia. Furthermore, we provide an overview of recent studies on the application of metabolomics to the assessment of the efficacy of traditional herbal products and common lipid-lowering medications.

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Metabolomics Analysis of Cell-Free Expression Systems Using Gas Chromatography-Mass Spectrometry

Cited by 2 publications

References 19 publications

Cell-Free Systems in Metabolomics

Cell-Free Systems in Metabolomics

The Application of Metabolomics in Hyperlipidemia: Insights into Biomarker Discovery and Treatment Efficacy Assessment

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