Metabolomics for exposure assessment and toxicity effects of occupational pollutants: current status and future perspectives

The CcpNmr Analysis Simulated Metabolomics Database (CASMDB): An Open-Source Collection of Metabolite Annotation Data for 1D1H NMR-Based Metabolomics

“…As such, a metabolomic profile is a particularly good representative of the phenotype of the sample under examination. Metabolomics studies typically aim to identify biomarkers of metabolic processes or disease and have applications in a wide variety of research interest including pharmaceuticals (Alarcon-Barrera et al ., 2022) personalised medicine (Di Minno et al ., 2022), nutrition (LeVatte et al ., 2021) microbiology (Zhao et al ., 2020), agriculture (Razzaq et al ., 2022), marine biology (Bayona, de Voogd and Choi, 2022) and toxicology (Dehghani et al ., 2022).…”

Tissue-specific sex difference in mouse eye and brain metabolome under fed and fasted states

“…Metabolome is a collection of metabolites such as carbohydrates, amino acids, nucleotides, fatty acids and vitamins in the cell or tissue, serving as substrates, products, cofactors, or ligands for biochemical reactions, nutrient transport and cell signaling 14 . These metabolites are not only the products of metabolic gene and protein expression, but also reflect interactions with the environment such as microbiome, diets and exposure [15][16][17] . Quantifying metabolites by metabolomics is increasingly important in eye research to identify tissue-specific metabolism in healthy ocular tissues and mechanisms or biomarkers in ocular diseases [18][19][20][21][22] .…”