Metabolomics for plant stress response

Shulaev, Vladimir; Cortes, Diego Fernando Marmolejo; Miller, Gad; Mittler, Ron

doi:10.1111/j.1399-3054.2007.01025.x

Cited by 600 publications

(416 citation statements)

References 67 publications

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“…The metabolomics approach has been applied in various areas of plant biology and ecology (Sardans et al, 2011;Weckwerth, 2011), where it has helped in understanding the regulation of pathways during plant-herbivore interactions (Jansen et al, 2008;Misra et al, 2010) and plant stress responses (Shulaev et al, 2008;Nakabayashi and Saito, 2015). What typically distinguishes metabolomics from targeted analyses or general metabolic profiling is the ambition to integrate with other omics sciences (Fiehn, 2002;Barah and Bones, 2015).…”

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confidence: 99%

Central Metabolic Responses to Ozone and Herbivory Affect Photosynthesis and Stomatal Closure

et al. 2016

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Plants have evolved adaptive mechanisms that allow them to tolerate a continuous range of abiotic and biotic stressors. Tropospheric ozone (O 3 ), a global anthropogenic pollutant, directly affects living organisms and ecosystems, including plant-herbivore interactions. In this study, we investigate the stress responses of Brassica nigra (wild black mustard) exposed consecutively to O 3 and the specialist herbivore Pieris brassicae. Transcriptomics and metabolomics data were evaluated using multivariate, correlation, and network analyses for the O 3 and herbivory responses. O 3 stress symptoms resembled those of senescence and phosphate starvation, while a sequential shift from O 3 to herbivory induced characteristic plant defense responses, including a decrease in central metabolism, induction of the jasmonic acid/ethylene pathways, and emission of volatiles. Omics network and pathway analyses predicted a link between glycerol and central energy metabolism that influences the osmotic stress response and stomatal closure. Further physiological measurements confirmed that while O 3 stress inhibited photosynthesis and carbon assimilation, sequential herbivory counteracted the initial responses induced by O 3 , resulting in a phenotype similar to that observed after herbivory alone. This study clarifies the consequences of multiple stress interactions on a plant metabolic system and also illustrates how omics data can be integrated to generate new hypotheses in ecology and plant physiology.

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Central Metabolic Responses to Ozone and Herbivory Affect Photosynthesis and Stomatal Closure

et al. 2016

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“…Metabolomics has been applied recently to physiological and ecological studies to assess the physiological status and functions of organisms, including their energetic and oxidative states; functions of growth, defense, storage, and reproduction; and mechanisms of stress avoidance and health (15)(16)(17)(18).…”

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Strong relationship between elemental stoichiometry and metabolome in plants

Rivas‐Ubach

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Pérez‐Trujillo

et al. 2012

Proc. Natl. Acad. Sci. U.S.A.

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Shifts in the elemental stoichiometry of organisms in response to their ontogeny and to changing environmental conditions should be related to metabolomic changes because elements operate mostly as parts of molecular compounds. Here we show this relationship in leaves of Erica multiflora throughout their seasonal development and in response to moderate experimental field conditions of drought and warming. The N/P ratio in leaves decreased in the metabolically active growing seasons, coinciding with an increase in the content of primary metabolites. These results support the growthrate hypothesis that states that rapidly growing organisms present low N/P ratios because of the increase in allocation of P to RNA. The foliar N/K and P/K ratios were lower in summer and in the drought treatment, in accordance with the role of K in osmotic protection, and coincided with the increase of compounds related to the avoidance of water stress. These results provide strong evidence of the relationship between the changes in foliar C/N/P/K stoichiometry and the changes in the leaf's metabolome during plant growth and environmental stress. Thus these results represent a step in understanding the relationships between stoichiometry and an organism's lifestyle.climate change | metabolomics | ecometabolomics | Mediterranean climate

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“…Species name abbreviations are as follows: At, Arabidopsis; Np, Nicotiana plumbaginifolia; St, potato (Solanum tuberosum); Ta, wheat (Triticum aestivum); Tp, Triticum polonicum; and Zm, maize. fleshy fruit arose as a mechanism to facilitate seed dispersal and promote the survival of the plant in everchanging environments (Coombe, 1976), the regulation of fruit ripening by external cues is of great importance in the plant's adaptation to environmental stresses (Shulaev et al, 2008). Given that OST1 is a critical mediator of ABA signaling, and that SnRK2s are tightly associated with plant stress signaling (Yoshida et al, 2002;Boudsocq et al, 2004;Umezawa et al, 2004;Kobayashi et al, 2005;Fujii et al, 2007;Shukla and Mattoo, 2008;Fujita et al, 2009;Hirayama et al, 2010;Kulik et al, 2011;Hrabak et al, 2013), we sought to identify the ortholog of OST1 in strawberry and to evaluate whether this protein contributes to the regulation of strawberry fruit development and ripening, and particularly whether it modulates fruit ripening in response to temperature.…”

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confidence: 99%