Metacognitive Training for Obsessive-Compulsive Disorder: a study protocol for a randomized controlled trial

Miegel, Franziska; Demiralay, Cüneyt; Moritz, Steffen; Wirtz, Janina; Hottenrott, Birgit; Jelinek, Lena

doi:10.1186/s12888-020-02648-3

Cited by 12 publications

(5 citation statements)

References 96 publications

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“…The pilot version of the MCT-OCD was highly accepted by patients 12 . In a subsequent randomized controlled trial the revised version of the MCT-OCD was compared to a wait-list control group with access to care as usual 13 .…”

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confidence: 99%

Session-specific effects of the Metacognitive Group Training for Obsessive–Compulsive Disorder: significant results for thought control

Miegel

Cludius

Hottenrott

et al. 2020

Sci Rep

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The investigation of the session-specific effects is central for the understanding of psychological interventions. For the present study, we investigated the session-specific effects of the Metacognitive Group Training for Obsessive–Compulsive Disorder (MCT-OCD), which was revised based on data of a pilot study. Thirty-four outpatients with OCD participated in the MCT-OCD once a week over 8 weeks. Different metacognitive beliefs (e.g., thought control) and cognitive beliefs (e.g., intolerance of uncertainty), OC symptoms, as well as associated comorbid symptoms were assessed before and after each session. Linear mixed effects models showed that patients’ obsessions and compulsions, thought control, the belief of being well informed about the disorder, and action fusion improved over the course of the training. The only session-specific effect emerged for thought control, which improved immediately after the respective module. We were able to replicate the findings of the pilot study and thus corroborate the session-specific effect of the module targeting thought control. Moreover, we generated information on the mode of action of the individual modules of the MCT-OCD that allows a more in-depth evaluation of the intervention. Notably, we were able to eliminate the adverse effects of the pilot version of the MCT-OCD. Trial Registration: German Clinical Trials Register (Deutsches Register Klinischer Studien [DRKS]; DRKS-ID: DRKS00013539; registration date: 22/02/2018).

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confidence: 99%

Session-specific effects of the Metacognitive Group Training for Obsessive–Compulsive Disorder: significant results for thought control

Miegel

Cludius

Hottenrott

et al. 2020

Sci Rep

Self Cite

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“…The authors determined that there was a session-specific effect for thought control only. Park et al 34 prospectively investigated whether metacognitions could be used to predict treatment response following initiation of serotonin reuptake inhibitors in patients with OCD. They followed 132 patients under serotonin reuptake inhibitor (SRI) treatment for 4 weeks with the Yale-Brown Obsession Compulsion Scale (Y-BOCS) and investigated the treatment response.…”

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confidence: 99%

Metacognitive Therapy in Patients with ObsessiveCompulsive Disorder: A review

Atmaca¹

2022

ALPHA PSYCHIATRY

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Metacognitive therapy is a relatively novel and growing psychotherapeutic approach. Within the last 20 years, several metacognitive-oriented therapy methods have been developed. They are metacognitive therapy which was developed by Wells, metacognitive training which was produced by Moritz et al. especially for patients with psychotic disorder, and metacognitive reflection and insight therapy for psychotic patients. Among them, the most structured one seems the metacognitive therapy. The main notion of metacognitive therapy is to alter the dysfunctional metacognitive interpretations and strategies underlying psychopathology. However, it should be emphasized that it has some fundamental differences from cognitive behavioral therapy because metacognitive therapy is a relatively new school of cognitive therapy, its effectiveness in the treatment of many psychiatric disorders continues to be evaluated intensively. Obsessive-compulsive disorder is one of these disorders. As obsessive-compulsive disorder is a lifelong disorder that causes significant loss of workforce and pharmacotherapy is sometimes insufficient, psychotherapeutic approaches are of great importance. In this context, exposure and response prevention still seems to be an important treatment option in terms of psychotherapeutic approaches. However, it is clear that a new approach is required in psychiatry practice in cases where exposure and response prevention and classical cognitive behavioral therapy are not sufficient and remain with residual symptoms. In this respect, metacognitive therapy can be an important alternative to fill this gap. However, more evidence needs to be created with studies with much larger samples.

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“…Poor insight, lack of motivation for treatment, and depression can interfere with OCD treatment and have been reported to correlate with OCD severity. [31][32][33] In the first place, the dropout rate of ERP for OCD is as high as 25%, 34 and it is assumed that patients with post-TBI OCD are more likely to experience treatment failure. In the present case, a more attentive approach to mood and motivation and more careful neuropsychoeducation for post-TBI sequelae might have allowed the patient to continue treatment and achieve greater improvement in OCD symptoms.…”

Section: Discussionmentioning

confidence: 99%

Obsessive–compulsive disorder after traumatic injury to the right frontal and left temporal lobes: A case report

Yoshioka,

Yamanashi,

Hayashi

et al. 2024

PCN Reports

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BackgroundObsessive–compulsive disorder (OCD) is a common neuropsychiatric disorder affecting many behaviors in daily life. Hyperactivity of the fronto‐striato‐thalamic circuit via the orbitofrontal cortex (OFC) is assumed to play a major role in the pathophysiology of OCD; however, its pathogenesis is not fully understood. Several reports have described the development of OCD after traumatic brain injury (TBI); however, the pathogenesis of post‐TBI OCD remains unknown. Moreover, patients with TBI often have a variety of sequelae, including cognitive dysfunction and mood disorders, which make the diagnosis and treatment of OCD more complex.Case presentationWe report the case of a 17‐year‐old Japanese male who developed OCD after traffic trauma. The patient developed a fear of contamination and checking compulsion after injuring his right OFC and left temporal lobe when he ran into a running truck during a suicide attempt. We believe that the patient's fear of contamination can be diagnosed as true post‐TBI OCD. However, his memory impairment was significant, and we considered his checking compulsion to be strongly influenced by cognitive dysfunction due to TBI. We attempted behavioral therapy for OCD; however, sufficient results were not achieved because of the interference from the sequelae of TBI.ConclusionIt is not rare for OCD symptoms to appear after TBI. Differentiating the OCD symptoms induced by brain injury or cognitive dysfunction associated with TBI is important to determine a treatment strategy.

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Metacognitive Training for Obsessive-Compulsive Disorder: a study protocol for a randomized controlled trial

Cited by 12 publications

References 96 publications

Session-specific effects of the Metacognitive Group Training for Obsessive–Compulsive Disorder: significant results for thought control

Session-specific effects of the Metacognitive Group Training for Obsessive–Compulsive Disorder: significant results for thought control

Metacognitive Therapy in Patients with ObsessiveCompulsive Disorder: A review

Obsessive–compulsive disorder after traumatic injury to the right frontal and left temporal lobes: A case report

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