2024
DOI: 10.1002/jmv.29802
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Metagenomic analysis of the gut virome in patients with irritable bowel syndrome

Pan Zhang,
Shiyang Ma,
Ruochun Guo
et al.

Abstract: Irritable bowel syndrome (IBS), a chronic functional gastrointestinal disorder, is recognized for its association with alterations in the gut microbiome and metabolome. This study delves into the largely unexplored domain of the gut virome in IBS patients. We conducted a comprehensive analysis of the fecal metagenomic data set from 277 IBS patients and 84 healthy controls to characterize the gut viral community. Our findings revealed a distinct gut virome in IBS patients compared to healthy individuals, marked… Show more

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