Metal Accumulation and Effect of Vitamin C and E
in Accumulated Heavy Metals in Different Tissues
in Common Carp (&lt;i&gt;Cyprinus carpio&lt;/i&gt;) Treated
with Heavy Metals

Sahiti, Hazbije; Bislimi, Kemajl; Rexhepi, Agim; Dalo, Enis

doi:10.15244/pjoes/103354

Cited by 15 publications

(26 citation statements)

References 15 publications

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“…This is also probably why the highest mean value of 37.55±0.03µg/ml in T4 was obtained in the gills of the fish in this case at the 8 th week of exposure for susteined up-regulation of the defence system of the fish at the highest level of concentration and duration; and that the presence of the vitamin may have reduced the burden in lower concentrations. In line with this, Sahiti et al [34] reported how supplementation of vitamins C and E either alone or jointly had significantly decreased (p<0.01; p<0.05) levels of accumulated heavy metals in investigated tissues compared to the control and exposed groups.…”

Section: Gsh Production Levels In C Gariepinus Exposed To Sub-lethal Concentrations Of Pb Toxicant and The Respective Supplemented Treatmmentioning

confidence: 65%

Evaluation of the ameliorative roles of vitamins A, C and E on reduced glutathione in Clarias gariepinus (Burchell, 1822) fingerlings exposed to lead nitrate

Po¹,

Fo²,

Av³

et al. 2021

GSC Adv. Res. Rev.

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The ever-increasing anthropogenic activities all over the world that usually led to release of plethora of pollutants such as lead calls for concern. In the present study the effects of lead nitrate on the production of antioxidants such as reduced glutathione (GSH) in C. gariepinus and how such effects can be ameliorated through administration of vitamins were investigated. C. gariepinus fingerlings (whose initial weight ranged from 3-11g) were exposed to sub-lethal concentrations of Pb (00, 26mg/L, 44mg/L, 61mg/L and 79mg/L) with replicate in each case. 26mg/L each of the vitamins were administered across all bud. Fresh concentrations of both toxicant and vitamins were administered every 72 hours for a period of 12 weeks every time the water medium was changed. The various treatments group include Pb (Pb only), PbVA (Pb+vitamin A), PbVC ((Pb+vitamin C) and PbVE (Pb+vitamin E) with T1-T4 and replicates in each case. 3 samples of the fish were randomly selected and sacrificed from each aquarium tank every 2 weeks of the exposure period. The gills, kidneys and liver were excised from these specimens and homogenized in sodium phosphate buffer. These were then assayed for GSH productions levels in each case. The data generated were subjected to one way analysis of variance and considered significant at P≤0.05. From the results: In the Pb only group, the mean values of the GSH produced in the liver of the control samples were significantly higher than other treatments. The highest mean values of 82.04±0.13µg/ml, 30.84±0.10µg/ml and 31.30±0.10µg/ml were obtained in the liver, kidney and gills of the fish, respectively. In fish samples exposed to PbVA group, the highest mean values of 23.57±0.10µg/ml, 58.74±0.07µg/ml and 52.72±0.07µg/ml were obtained in the liver, kidney and gills, respectively. In C. gariepinus exposed to PbVC group, the highest mean values obtained in the liver, kidneys and gills were 25.79±0.07µg/ml, 28.40±0.13µg/ml and 37.55±0.03µg/ml, respectively. In PbVE group, the highest mean value of 57.21±0.03µg/ml, 83.51±0.07µg/ml and 63.29±0.07µg/ml were btained in the liver, kidneys and gills, respectively. The liver of the samples exposed to Pb only group displayed higher level of response to the toxicant with the highest GSH produced in the lowest concentration in comparison to other fish organs. In the PbVA group the response was more in the kidney in the highest concentration. There were general low levels of production in all organs of the fish in the PbVC group. The kidneys of the PbVE group exhibited the highest level of GSH production in comparison to other organs. The kidneys and liver of C. gariepinus in this research were fully engaged in mitigating the effects of the toxicant in the presence of the vitamins. Administration of higher concentrations of the vitamins could enhance better understanding of the ameliorative roles of the vitamins against the deleterious effects of the toxicant.

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Section: Gsh Production Levels In C Gariepinus Exposed To Sub-lethal Concentrations Of Pb Toxicant and The Respective Supplemented Treatmmentioning

confidence: 65%

Evaluation of the ameliorative roles of vitamins A, C and E on reduced glutathione in Clarias gariepinus (Burchell, 1822) fingerlings exposed to lead nitrate

Po¹,

Fo²,

Av³

et al. 2021

GSC Adv. Res. Rev.

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show abstract

“…Another important finding was that, groups of fish exposed to the same sub-lethal concentrations of ZnO (bulk particles or nanoparticles) and supplemented with vitamins (E + C) have a significant decrease (P0.05) in accumulated Zn levels in muscle and gill tissue compared to groups without supplementation. This may be due to the chelating role of vitamins (E + C) in reducing Zn content in investigated tissues of O. niloticus fish as confirmed by Sahiti et al (2020) who stated that supplementation of vitamins C and E either alone or jointly had significantly decreased (p<0.01; p<0.05) levels of accumulated heavy metals in investigated tissues of common carp compared to the control and exposed groups. Moreover, our results illustrated that the values of accumulated Zn in muscle and gill tissues of supplemented groups returned to similar levels established in the control at low concentrations but still higher than control at the high sub-lethal concentrations of ZnO BPs or ZnO NPs.…”

Section: )mentioning

confidence: 68%

The protective role of vitamins (E + C) on Nile tilapia (Oreochromis niloticus) exposed to ZnO NPs and Zn ions: Bioaccumulation and proximate chemical composition

Mohamed

Ghannam

Soliman

2022

Annals of Animal Science

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The accumulation potency of zinc nanoparticles in Nile tilapia (Oreochromis niloticus) were previously studied but their impacts on proximate chemical composition in muscle tissue by describing the dose-dependent accumulation and the protective role of vitamins (E + C), have not been investigated. Therefore, this study was carried out to assess the protective role of vitamins (E + C) on Zn accumulation in muscle and gill tissues of O. niloticus exposed to three sublethal concentrations (1/8 LC50, 1/4 LC50, and 1/2 LC50) of zinc oxide nanoparticles (ZnO NPs) compared to zinc oxide bulk particles (ZnO BPs) as well as their effects on the induced chemical composition alterations for different experimental periods (7, 14, 21, and 28 day). The data displayed that fish exposed to the different sublethal concentrations of ZnO NPs or ZnO BPs have a significant increase (p<0.05) in Zn ions accumulation in muscle and gill tissues compared to control group but Zn was accumulated in gill tissue higher than muscle tissue at all exposure periods. Also, Zn accumulation was higher in fish tissues exposed to ZnO NPs than ZnO BPs. On the other hand, groups supplemented with vitamins (E + C) showed a significant decreasing (p<0.05) in accumulated Zn levels compared to groups without supplementation. The values of these supplemented groups returned to similar levels established in the control at low concentrations but still higher than control at the high concentrations. Furthermore, the results showed that moisture and ash content slightly increased while protein and fat decreased in fish exposed to ZnO NPs or ZnO BPs compared to control group. In conclusion, the findings supported that a combination of vitamins (E + C) reduced Zn accumulation and ameliorated chemical composition alterations in O.niloticus fish.

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“…Vitamin C has a role in tissue repair, protein formation, inactivation of toxic metals and protection of other vitamins (such as A and E), DNA from the harmful effects of oxidation (Hamza, 2017). In a study conducted by Sahiti et al (2020), it was reported that vitamin C reduced the heavy metal accumulation in the tissues. Due to these properties of vitamin C, various concentrations of vitamin C (25, 50 and 75 ppm) were added to the LB medium containing cadmium, in order to reduce the negative of cadmium.…”

Section: Resultsmentioning

confidence: 99%

Combine Effect of Vitamin C and Cadmium on the Aminoacid Content of Citrobacter Freundii

Ibrahim

Çakmak

Özer

et al. 2021

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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In this study, Citrobacter freundii was grown in LB medium containing different concentrations of cadmium. Then, vitamin C were added to the medium containing cadmium and amino acids content of bacteria were determined by HPLC. It was observed that, the amount of amino acids in C. freundii grown in LB medium, containing 75, 100 and 125 ppm cadmium were compared with the control, the amounts of alanine, arginine, asparagine, aspartic acid, cysteine, glycine, histidine, isoleucine, leucine, lysine, phenylalanine, proline, threonine, tyrosine and valine increased (p<0.05), glutamic acid, glutamine, methionine, serine and tryptophan levels were decreased p<0.05). With the addition of vitamin C to the growth medium of bacteria containing cadmium, showed that some of the amino acids concentrations increasing, rest of the amino acid studied were observed to be decreasing. From these findings, it can be said that the negative effect of cadmium on C. freundii is reduced by the addition of vitamin C to the medium. In short vitamin C reversed the effect of cadmium on the amino acid content of bacteria.

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Metal Accumulation and Effect of Vitamin C and E in Accumulated Heavy Metals in Different Tissues in Common Carp (<i>Cyprinus carpio</i>) Treated with Heavy Metals

Cited by 15 publications

References 15 publications

Evaluation of the ameliorative roles of vitamins A, C and E on reduced glutathione in Clarias gariepinus (Burchell, 1822) fingerlings exposed to lead nitrate

Evaluation of the ameliorative roles of vitamins A, C and E on reduced glutathione in Clarias gariepinus (Burchell, 1822) fingerlings exposed to lead nitrate

The protective role of vitamins (E + C) on Nile tilapia (Oreochromis niloticus) exposed to ZnO NPs and Zn ions: Bioaccumulation and proximate chemical composition

Combine Effect of Vitamin C and Cadmium on the Aminoacid Content of Citrobacter Freundii

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