To evaluate artifact reduction by virtual monoenergetic images (VMI) and metal artifact reduction algorithms (MAR) as well as the combination of both approaches (VMI MAR) compared to conventional CT images (CI) as standard of reference. In this retrospective study, 35 patients were included who underwent spectral-detector CT (SDCT) with additional MAR-reconstructions due to artifacts from coils or clips. CI, VMI, MAR and VMI MAR (range: 100-200 keV, 10 keV-increment) were reconstructed. Region-of-interest based objective analysis was performed by assessing mean and standard deviation of attenuation (HU) in hypo-and hyperdense artifacts from coils and clips. Visually, extent of artifact reduction and diagnostic assessment were rated. Compared to CI, VMI â„ 100 keV, MAR and VMI MAR between 100-200 keV increased attenuation in hypoattenuating artifacts (CI/VMI 200keV /MAR/VMI MAR200keV , HU: â77.6 ± 81.1/â65.1 ± 103.2/â36.9 ± 27.7/â21.1 ± 26.7) and decreased attenuation in hyperattenuating artifacts (HU: 47.4 ± 32.3/42.1 ± 50.2/29.5 ± 18.9/20.8 ± 25.8). However, differences were only significant for MAR in hypodense and VMI MAR in hypo-and hyperdense artifacts (p < 0.05). Visually, hypo-and hyperdense artifacts were significantly reduced compared to CI by VMI â„140/100keV , MAR and VMI MARâ„100keV. Diagnostic assessment of surrounding brain tissue was significantly improved in VMI â„100keV , MAR and VMI MARâ„100keV. The combination of VMI and MAR facilitates a significant reduction of artifacts adjacent to intracranial coils and clips. Hence, if available, these techniques should be combined for optimal reduction of artifacts following intracranial aneurysm treatment. Intracranial aneurysms are a common vascular disorder with a prevalence of approximately 4%, which can be expected to increase due to an ageing population 1,2. In case of rupture they are associated with a mortality risk of up to 50% [1]. Ruptured as well as unruptured aneurysms are commonly treated with surgical clipping or endovascular coiling 3,4. Postoperative imaging is pivotal to detect postoperative complications and ensure therapy success for which computed tomography (CT) is frequently applied besides digital subtraction angiography and magnetic resonance imaging 5. However, evaluation of brain parenchyma adjacent to clips and coils is often impaired by metal artifacts. Artifacts commonly appear as hypo-and hyperdense areas surrounding the metal material. These kind of artifacts result from a combination of beam-hardening caused by absorption of low energetic photons 6,7 , photon starvation resulting from complete absorption of all photons 7,8 , and scatter artifacts that can occur due to greater attenuation differences, e.g. soft tissue and dense metal material 9. Combined, these effects can result in strong interferences that may impair depiction and interpretation of surrounding brain tissue. Therefore, evaluation of post-interventional complications, such as tissue damage, haemorrhage, infarction and oedema may be limited 10. Further, any futur...