Metal‐Catalyzed Hydroboration Reactions of Alkyne and Subsequent Asymmetric Transformation

Abstract

Hydroboration of alkynes provides a most straightforward, atom‐economical, and convenient methodology to access alkenylboronic esters which have a wide range of applications in organic synthesis. Several efficient successful metal‐catalyzed methods have been developed for selective hydroboration of alkynes through steric and electronic effects, as well as through efficient design of the nature of the ligand coordinating the metal. This chapter mainly covers the metal‐catalyzed hydroboration reactions of alkynes and subsequent asymmetric transformations (such as hydrogenation, hydroboration, hydrosilylation, and hydroallylation).