Metal complexes of virus inhibitors. Part III. Coordination properties of 1-n-propyl-2-α-hydroxybenzylbenzimidazole and the X-ray crystal structure of Ni(C17H18N2O)2(C17H17N2O)1(ClO4)1

Goodgame, M.; Holt, Steven D.; Piggott, Brian; Williams, David J.

doi:10.1016/s0020-1693(00)80689-1

Cited by 8 publications

(2 citation statements)

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“…For the antiviral action and anthelmintic activity of substituted benzimidazoles, see: Goodgame et al (1985). Related structures have been reported: thiabendazole (Trus & Marsh, 1973); thiabendazolium nitrate (Murugesan et al, 1998;Devereux et al, 2004); thiabendazolium perchlorate (Stanley et al, 2002); thiabendazolium halide dihydrates (Prabakaran et al, 2000).…”

Section: Related Literaturementioning

confidence: 99%

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2-(1,3-Thiazol-4-yl)benzimidazolium nitrate monohydrate

Flores-Álamo¹,

González-Martínez²,

Castillo‐Blum³

2010

Acta Cryst E

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In the title compound, C10H8N3S+·NO3 −·H2O, one of the N atoms of the benzimidazole unit is protonated, unlike than that in the thiazole group. This protonation leads to equalization of the bond angles at the two N atoms of the benzimidazole group. The benzimidazole and thiazole systems are almost coplanar, forming a dihedral angle of 0.5 (2)°. In the crystal, the nitrate anion and water molecule bridge the thiabendazolium cations through N—H⋯O and O—H⋯O hydrogen bonds, leading to a supramolecular network based on an infinite one-dimensional chain using [001] as base vector.

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Section: Related Literaturementioning

confidence: 99%

“…Substituted benzimidazoles show antiviral action and anthelmintic activity. This has been attributed to their metalchelating ability (Goodgame et al, 1985). Thiabendazole is a broad-spectrum anthelmintic compound useful in the treatment of human and animal parasitic diseases.…”

Section: S1 Commentmentioning

confidence: 99%