2015
DOI: 10.1007/s11094-015-1184-1
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Metal Complexes with Ethylenediaminedicarboxylic Acids and Their Derivatives, Promising Pharmacological and Diagnostic Agents (Review)

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Cited by 4 publications
(2 citation statements)
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“…Recent studies aim to develop new drugs that can be administered orally for the treatment of diabetes [2,3]. Coordination compounds have demonstrated to inhibit enzymes that play a major role in modulating insulin sensitivity [4,5]. The design of these novel materials based on metal ions could be an excellent tool to improve the distribution and, therefore, the effectiveness of metals as oral anti-diabetic agents in the treatment of diabetes mellitus, giving an alternative to traditional insulin therapy.…”
Section: Introductionmentioning
confidence: 99%
“…Recent studies aim to develop new drugs that can be administered orally for the treatment of diabetes [2,3]. Coordination compounds have demonstrated to inhibit enzymes that play a major role in modulating insulin sensitivity [4,5]. The design of these novel materials based on metal ions could be an excellent tool to improve the distribution and, therefore, the effectiveness of metals as oral anti-diabetic agents in the treatment of diabetes mellitus, giving an alternative to traditional insulin therapy.…”
Section: Introductionmentioning
confidence: 99%
“…Chemistry of ethylenediaminedicarboxylic acid(s) and their derivatives expanded the serie of organic compounds with interesting biological and pharmacological profile. 1 This class of compounds offers multiple advantages, from chemical as well as from medicinal point of view. In the first place, N-containing organic ligands represent a promising base for designing suitable metal-based drug.…”
mentioning
confidence: 99%