Metal(II) complexes of bioactive aminonaphthoquinone-based ligand: synthesis, characterization and BSA binding, DNA binding/cleavage, and cytotoxicity studies

Eco-friendly Synthesis of Schiff base Mn(II) and Cu(II) Complexes: Antimicrobial, Antifungal, Molecular Docking and Anticancer Studies

“…The plane deformation and C-C stretching frequencies of oxalate ion present in their particular frequencies of IR spectra (Figure -4). [24], [25] These facts con rm the entry of oxalate ions in the coordination sphere through bridging mode by two oxygen atoms (Table-3). Furthermore, the conclusive evidence of the coordination of the Schiff base ligand with metal ions was shown by the appearance of new M-N low weak frequency at 487 cm − 1 and M-O frequency at 399 cm − 1 and 380 cm-1for Mn(II) complex.…”

“…Further in the Cu(II) complex, the Cu-N appeared at 481cm − 1 and Cu-O 392 cm − 1 , 350 cm − 1 which have been assigned in the FAR-IR spectral study. [24][25][26]…”

“…The observed magnetic moment of the complex at room temperature is 5.90 BM witnessing the high spin octahedral geometry as well as paramagnetic nature. [24][25][26] The electronic absorption spectrum of the Cu(II) complex shows a strong band at 319 nm which can be assigned to n→π* and the LMCT band exhibited at 382 nm. Thus the visible region of spectrum exhibited the d-d electronic transition at 712 nm which are assigned to 2 Eg (D)→2T 2 g(D).…”

Natural-product-inspired design and synthesis of thiolated coenzyme Q analogs as promising agents against Gram-positive bacterial strains: insights into structure–activity relationship, activity profile, mode of action, and molecular docking

“…18 It is worth noting that some 1,4-quinones have also found use as functional ligands for transition metals. [19][20][21][22] What's more, the Coenzyme Qn (CoQn) family, also named as the ubiquinones, has occupied a unique position in the design and synthesis of novel biologically active lead molecules that exert remarkable medicinal activity. 23 Besides of versatile properties, not surprisingly, ubiquinone participating in the cellular aerobic respiration process, 24 plastoquinone and phylloquinone serving as electron acceptors in electron transport chains in photosynthesis, and vitamin K participating coagulation process and preventing bleeding have also a 1,4-quinone motif.…”

“…18 It is worth noting that some 1,4-quinones have also found use as functional ligands for transition metals. 19–22…”