Metal organic framework-based polymeric hydrogel: A promising drug delivery vehicle for the treatment of breast cancer

Pandya, Ishani; Kumar, Sugam; Aswal, Vinod K.; El Seoud, Omar; Assiri, Mohammed A.; Malek, Naved

doi:10.1016/j.ijpharm.2024.124206

International Journal of Pharmaceutics

2024

DOI: 10.1016/j.ijpharm.2024.124206

|View full text |Cite

Metal organic framework-based polymeric hydrogel: A promising drug delivery vehicle for the treatment of breast cancer

Ishani Pandya,

Sugam Kumar,

Vinod K. Aswal

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

References 82 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Preparation and Characterization of Low‐Voltage Responsive Nanocomposite Shape‐Changing Hydrogels/Carbon Nanofibers With Enhanced Mechanical Properties

Li,

Ma,

et al. 2024

Journal of Polymer Science

View full text Add to dashboard Cite

High‐voltage responsiveness and poor mechanical properties hindered the practical applications of electro‐induced shape‐changing hydrogels (EISCHs). In previous work, mechanical properties were improved simply by increasing the degree of crosslinking, which resulted in reduced deformation capacity. Therefore, the nanocomposite technique of reinforcing nondeformable hydrogels' mechanical properties was introduced into EISCHs, resulting in the successful synthesis of Poly (N‐isopropylacrylamide‐co‐5‐acrylamido‐1,10‐phenanthroline bis (1,10‐phenanthroline) iron (II))/hydrophilic‐treated hydroxylated carbon nanofibers (P(NIPAM‐Fe(phen)3)/HMWCNFs) nanocomposite shape‐changing hydrogel that exhibits outstanding mechanical properties, doesn't have its deformation ability weakened and possesses low‐voltage responsiveness in this work. The impact of various hydrophilic‐treated hydroxylated carbon nanofibers (HMWCNFs) content on hydrogels' structure, swelling, crosslinking, mechanics and electro‐induced shape‐changing properties was investigated. As the HMWCNFs content increased (0.2%–1.0%), the tensile and compressive strengths increased, marking 6.67 times and 2.91 times rise over hydrogel without HMWCNFs. The deformation ability of P(NIPAM‐Fe(phen)3/HMWCNFs) hydrogel was higher than without HMWCNFs at minimum response voltage 10 V. The physical entanglements and hydrogen bonding between HMWCNFs and polymer chains reduced adhesion energy and provided energy dissipation. HMWCNFs, as a conductive filler, facilitated electron transfer. The hydrogel swelled and shrank due to the transition between 5‐acrylamido‐1,10‐phenanthroline bis (1,10‐phenanthroline) iron (II) (Fe(phen)3) network iron (II) and iron (III) states under low‐voltage stimulation.

show abstract

Preparation and Characterization of Low‐Voltage Responsive Nanocomposite Shape‐Changing Hydrogels/Carbon Nanofibers With Enhanced Mechanical Properties

Li,

Ma,

et al. 2024

Journal of Polymer Science

View full text Add to dashboard Cite

show abstract

Self-healable, stimuli-responsive bio-ionic liquid and sodium alginate conjugated hydrogel with tunable Injectability and mechanical properties for the treatment of breast cancer

Pansuriya,

Patel,

Singh

et al. 2024

International Journal of Biological Macromolecules

View full text Add to dashboard Cite

Synthesis of copper hexaferrite magnetic nanoparticles based on carboxymethyl cellulose modified with polyacrylic acid (CMC/PAA/CuFe12O19) for loading and release of Levothyroxine

Javidan,

Gharbani

2024

International Journal of Biological Macromolecules

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Metal organic framework-based polymeric hydrogel: A promising drug delivery vehicle for the treatment of breast cancer

Cited by 4 publications

References 82 publications

Preparation and Characterization of Low‐Voltage Responsive Nanocomposite Shape‐Changing Hydrogels/Carbon Nanofibers With Enhanced Mechanical Properties

Preparation and Characterization of Low‐Voltage Responsive Nanocomposite Shape‐Changing Hydrogels/Carbon Nanofibers With Enhanced Mechanical Properties

Self-healable, stimuli-responsive bio-ionic liquid and sodium alginate conjugated hydrogel with tunable Injectability and mechanical properties for the treatment of breast cancer

Synthesis of copper hexaferrite magnetic nanoparticles based on carboxymethyl cellulose modified with polyacrylic acid (CMC/PAA/CuFe12O19) for loading and release of Levothyroxine

Contact Info

Product

Resources

About