Metal pollutants induced peroxidase activity in different body tissues of freshwater fish, Labeo rohita

Javed, Muhammad; Abbas, Khalid; Ahmed, Tanveer; Abdullah, Sajid; Naz, Huma; Amjad, Hina

doi:10.1016/j.enceco.2020.09.001

Cited by 12 publications

(5 citation statements)

References 19 publications

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“…Cell viability and inhibition increase with an increasing concentration of zinc oxide nanoparticles [ 129 ]. ZnO NPs have an electrostatic characteristic that allows them to deliberately target cancerous cells without damaging normal cells [ 130 , 131 ]. The abundant presence of negatively charged phospholipids on the surface of cancer cells causes electrostatic interaction with zinc oxide nanoparticles.…”

Section: Anticancer Activity Of Zinc Nanoparticlesmentioning

confidence: 99%

Mechanistic Approaches to the Application of Nano-Zinc in the Poultry and Biomedical Industries: A Comprehensive Review of Future Perspectives and Challenges

et al. 2023

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Bio-fortification is a new, viable, cost-effective, and long-term method of administering crucial minerals to a populace with limited exposure to diversified foods and other nutritional regimens. Nanotechnology entities aid in the improvement of traditional nutraceutical absorption, digestibility, and bio-availability. Nano-applications are employed in poultry systems utilizing readily accessible instruments and processes that have no negative impact on animal health and welfare. Nanotechnology is a sophisticated innovation in the realm of biomedical engineering that is used to diagnose and cure various poultry ailments. In the 21st century, zinc nanoparticles had received a lot of considerable interest due to their unusual features. ZnO NPs exhibit antibacterial properties; however, the qualities of nanoparticles (NPs) vary with their size and structure, rendering them adaptable to diverse uses. ZnO NPs have shown remarkable promise in bio-imaging and drug delivery due to their high bio-compatibility. The green synthesized nanoparticles have robust biological activities and are used in a variety of biological applications across industries. The current review also discusses the formulation and recent advancements of zinc oxide nanoparticles from plant sources (such as leaves, stems, bark, roots, rhizomes, fruits, flowers, and seeds) and their anti-cancerous activities, activities in wound healing, and drug delivery, followed by a detailed discussion of their mechanisms of action.

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Section: Anticancer Activity Of Zinc Nanoparticlesmentioning

confidence: 99%

Mechanistic Approaches to the Application of Nano-Zinc in the Poultry and Biomedical Industries: A Comprehensive Review of Future Perspectives and Challenges

et al. 2023

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“…leading to the accumulation of oxidatively damaged products on the long-term. In sh collected at rivers polluted by heavy metal, the sh accumulated zinc, chromium, nickel, cobalt and copper with a concomitant rise in Per activity in the liver, gills and muscles (Javed et al, 2020). This suggests that these metals lead to H 2 O 2 perhaps at the expense of antioxidant levels (i.e., reduced antoxidant capacity)…”

Section: Introductionmentioning

confidence: 99%

Screening of municipal effluents with the peroxidase toxicity assay

Gagné,

André,

Smyth

2024

Preprint

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The peroxidase (Per) reaction is a quick and inexpensive biosensor for the screening of environmental contaminants. The purpose of this study was to screen various municipal wastewaters before and after 7 different types of treatment processes. Wastewater samples before (influents) and after the following treatments (effluent) were tested using the Per activity test: advanced biofiltration, biofiltration, aerated lagoons, secondary aeration sludge, trickling filter, secondary membrane filtration, and primary. The influents and effluents were collected for 3 days composites and concentrated to 500 X on a reverse-phase (C18) extraction cartridge. The ethanol extracts were examined for dissolved organic carbon, plastic-like materials, polyaromatic hydrocarbons and polystyrene nanoplastics. The samples were then tested using the Per reaction alone and in the presence of DNA to detect DNA binding agents. The result show that population size tended to increase Per activity and 60% of the effluents decreased Per activity leading to H2O2 persistence. More advanced treatments (biofiltration, membrane biofiltration, secondary aeration) produced stronger changes from the corresponding untreated influents. The addition of DNA during the Per reaction revealed that population size had no influence and that significant changes occurred in 60% of treated effluents suggesting release of genotoxic compounds in the aquatic environment by most treated wastewaters. The toxic implications of these results to aquatic organisms are discussed.

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“…Monitoring contaminants is one of the advantages of using fish in physiological investigations, since fish are one of the most vulnerable animals to the long-term effects of pollution (Zeng et al 2012;Olusola & Festus, 2015;Malakootian et al, 2016;Mortazavi et al, 2016). Moreover, fish are recognized as the best animal protein source; humans ingest fish for they include important elements, such as vitamins and fatty acids (unsaturated), and other essential minerals required for proper growth and development (Javed et al, 2020). Oreochromis aureus, blue tilapia, is a freshwater species in the Cichlidae family that has developed tolerance to brackish water, This species, with its historical roots in northern Africa and the Middle East, looks blue-gray and abdominal pinkwhite; it can be found in abundance in lagoons and rivers.…”

Section: Introductionmentioning

confidence: 99%

Carcinogenic and Human Risk Assessments, Trace Element Concentrations, Proximate Composition, and Liver Antioxidants of Three Commercial Tilapia Fish Species from Manzalah Wetland, Egypt

Mourad¹,

Abdel-Kader²

2022

Egypt. J. of Aquatic Biolo. and Fish.

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Manzala Wetland is Egypt's largest ecosystem and the country's secondlargest lake overall. In 2016, in line with Egypt's Vision 2030, the Egyptian government developed a strategy to boost the economic potential of northern lakes, which includes Manzalah Wetland. The focus of this research was to test for trace elements including lead (Pb), mercury (Hg), arsenic (As), and aluminum (Al) in the muscle tissue of three commercially significant tilapia fish species gathered with the help of Manzalah Lake fishermen in 2018. Pb and Hg were largely above the permissible level of Food Agricultural Organization FAO, World Health Organization WHO, and Commission Regulation EU. The proximate chemical composition and antioxidants of the liver were estimated. The results showed that the highest mean carbohydrate, and fats, found in O. aureus, the water content and ash in T. zillii, and protein concentrations was in S. galilaeus. The results of the current investigation showed that, S. galilaeus had the highest levels of activity of liver antioxidants CAT, Gpx and GR, SOD in T. zillii, as well as GSH level in O. aureus. The metal with the highest concentration was Pb in O.aureus (2.85±0.2), whereas the least amount was Hg in S. galilaeus (0.55±0.04). Hg levels in O. aureus, S. galilaeus, and T. zillii ingested by children, youth, and adults showed the lowest of all metals, but they were higher than the permissible levels, indicating a risk to people's health from consuming the examined hazardous element through the diet of the three fish species. The target hazard quotient (THQ ) value of As in T. zillii intake by a child demonstrated the highest value ranging from (21 a day to 147 a week), while the THQ value of Pb in S. galilaeus intake by an adult showed the least value of THQ (0.73 a day or 5.11 a week). Based on the values of the total target hazard quotient (TTHQ) of the three fish samples for children, youth and adults, ingesting these fish poses a high non-carcinogenic risk. Tilapia zillii ingested by children recorded the highest degree of carcinogenic risk (CR) (9.45E-03 a day or 6.62E-02 a week); whereas, S. galilaeus in adults recorded the lowest level of CR (2.19E-05 a day or 1.54E-04 a week). The THQs and CRs values of Pb, Al, As, and Hg in the three examined species were greater than one, surpassing the Environmental Protection Agency recommendation (US EPA) acceptable limits. This finding demonstrates that, daily or weekly eating of these species could pose a high risk of non-carcinogenic and carcinogenic consequences to humans; thus, the fishes of the lagoon may be dangerous for human consumption in general.

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Metal pollutants induced peroxidase activity in different body tissues of freshwater fish, Labeo rohita

Cited by 12 publications

References 19 publications

Mechanistic Approaches to the Application of Nano-Zinc in the Poultry and Biomedical Industries: A Comprehensive Review of Future Perspectives and Challenges

Mechanistic Approaches to the Application of Nano-Zinc in the Poultry and Biomedical Industries: A Comprehensive Review of Future Perspectives and Challenges

Screening of municipal effluents with the peroxidase toxicity assay

Carcinogenic and Human Risk Assessments, Trace Element Concentrations, Proximate Composition, and Liver Antioxidants of Three Commercial Tilapia Fish Species from Manzalah Wetland, Egypt

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