Metal Sensitivity in Patients Treated for Tibial Fractures with Plates of Stainless Steel

Cramers, M; Lucht, Ulf

doi:10.3109/17453677708988763

Cited by 117 publications

(46 citation statements)

References 7 publications

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“…All the other samples, independent of the producer, were always found to contain a consistently low percentage of additions, such as nickel, following their further processing into rods of different sizes [diameters between 6 and 60 mm were analyzed]. Numerous publications deal with hypersensitivity reactions to osteosynthesis materials used in the treatment of fractures, the majority of these materials being stainless steel implants [7,19,32]. An immunological response to metals [partly as an exaggerated allergic reaction] is discussed to be the cause of impaired wound healing or the delayed healing of fractures [19].…”

Section: Discussionmentioning

confidence: 99%

Titanium allergy or not? "Impurity" of titanium implant materials

Harloff¹,

Hönle²,

Holzwarth³

et al. 2010

Health

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For patients suffering from allergies to nickel, chrome and cobalt, titanium implants are the implants of choice. Nevertheless, titanium implant sensitivity has been reported in the form of "allergies" and an increasing number of patients are confused. This paper aims to use spectral analysis as a diagnostic tool for analyzing different titanium implant alloys in order to determine the percentage of the alloy components and additions that are known to cause allergies. Different materials, such as sponge titanium, TiAl6Nb7, Ti21SRx, TiAl6V4 %. This paper demonstrates that all the investigated implant material samples contained a low but consistent percentage of components that have been associated with allergies. For example, low nickel contents are related to the manufacturing process and are completely dissolved in the titanium grid. Therefore, they can virtually be classified as "impurities". Under certain circumstances, these small amounts may be sufficient to trigger allergic reactions in patients suffering from the corresponding allergies, such as a nickel, palladium or chrome allergy.

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Section: Discussionmentioning

confidence: 99%

Titanium allergy or not? "Impurity" of titanium implant materials

Harloff¹,

Hönle²,

Holzwarth³

et al. 2010

Health

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“…Биомеханически и анатомически обоснованные конструкции с условиями минимальной инва зивности и стабильности фиксации ежедневно пополняют арсенал врача. Однако аллергическая реакция на металл становится причиной неудачи применения даже самого обоснованного имплан тата [8,9]. Одним из направлений профилакти УДК 616.428-053: 616-089.84-06 Морфофункциональное состояние регионарных лиМфатических узлов в условиях интраМедуллярного остеосинтеза фиксатораМи с покрытиеМ на основе сверхтвердых соединений И.Ф.…”

Section: Introductionunclassified

Morphofunctional Status of Regional Lymph Nodes in Conditions of Intramedullary Osteosynthesis by Retainers With Coat Based on Superhard Compounds

Фуатович

Биктемировна

Владимировна

et al. 2014

Traumatology and Orthopedics of Russia

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Objective: to evaluate the morphofunctional state of the popliteal lymph nodes of the operated and intact pelvic rabbit limbs in conditions of intramedullary fixation of the tibia fracture with the implant coated with titanium nitride and hafnium. A morphological study of two groups of experimental animals was conducted. Osteoclasis of tibia and subsequent osteosynthesis with medical steel needles coated with and without titanium nitride and hafnium was made. In the lymph nodes of the animals in the comparison group both inflammatory (acute and chronic lymphadenitis) and immunomorfologycal (hyperplasia of T-and B-dependent areas, sinus histiocytosis) reactions were observed, with the latter being more common in the operated limb, and the inflammatory - in the intact one. The obtained data have proved the feasibility of using metal structures coated with nitrides of group IV metals (titanium and hafnium) for external osteosynthesis.

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“…The association between metal implants and metal sensitivity is well documented, although, unfortunately, reactions are relatively unpredictable, poorly understood, and highly debated [6][7][8]. Dermal hypersensitivity to metal is common and can affect up to 15% of the population [9].…”

Section: The Rising Potential Impact Of Metal Hypersensitivitymentioning

confidence: 99%

Hypersensitivity Reactions to Implanted Metal Devices: Facts and Fictions

2016

J Investig Allergol Clin Immunol

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The use of metals in the medical field has become increasingly prevalent over the past few decades. Patients find themselves being exposed to metals in a variety of ways, ranging from external exposure to instruments such as the stainless steel in surgical blades to internal exposure via medical devices being implanted in their bodies. There has been growing interest in the possibility of developing hypersensitivity reactions to constituent metals in medical implant devices, both in cutaneous and systemic forms. Hypersensitivity reactions to metals are uncommon, but they are reported and require appropriate evaluation and management, particularly if they are symptomatic. In view of the lack of consensus in the field on the appropriate steps to evaluate and manage patients with suspected metal hypersensitivity reactions, this review aims to analyze current evidence on hypersensitivity reactions to metallic implants in orthopedic surgery, endovascular surgery, obstetrics and gynecology, and dental surgery. Key words: Metal hypersensitivity. Metallic implants. ResumenEl empleo de metales dentro de la medicina ha ido aumentando de forma progresiva en las últimas décadas. Los pacientes se exponen a metales de diferentes formas desde fuentes externas, como instrumental quirúrgico como el presente en las hojas de acero de los bisturíes, hasta implantes metálicos. Como consecuencia de ello se está produciendo un interés creciente por la posibilidad de desarrollar reacciones de hipersensibilidad a metales presentes en los materiales y objetos implantados, tanto en forma de reacciones cutáneas como sistémicas. Las reacciones de hipersensibilidad a metales no son frecuentes, pero pueden desarrollarse, y por ello, requieren de un diagnóstico y tratamiento adecuado, especialmente en aquellos pacientes que desarrollen síntomas. No existe un consenso en el proceso diagnóstico ni en el tratamiento de estas reacciones en los pacientes con sospecha de alergia a metales. Esta revisión tiene por objeto actualizar la evidencia existente sobre las reacciones de hipersensibilidad a implantes metálicos en cirugía ortopédica, cirugía endovascular, cirugía obstétrica y ginecológica (OB-GYN) así como la dental. Palabras clave: Hipersensibilidad a metales. Implantes metálicos.

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Metal Sensitivity in Patients Treated for Tibial Fractures with Plates of Stainless Steel

Cited by 117 publications

References 7 publications

Titanium allergy or not? "Impurity" of titanium implant materials

Titanium allergy or not? "Impurity" of titanium implant materials

Morphofunctional Status of Regional Lymph Nodes in Conditions of Intramedullary Osteosynthesis by Retainers With Coat Based on Superhard Compounds

Hypersensitivity Reactions to Implanted Metal Devices: Facts and Fictions

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Metal Sensitivity in Patients Treated for Tibial Fractures with Plates of Stainless Steel

Cited by 117 publications

References 7 publications

Titanium allergy or not? &quot;Impurity&quot; of titanium implant materials

Titanium allergy or not? &quot;Impurity&quot; of titanium implant materials

Morphofunctional Status of Regional Lymph Nodes in Conditions of Intramedullary Osteosynthesis by Retainers With Coat Based on Superhard Compounds

Hypersensitivity Reactions to Implanted Metal Devices: Facts and Fictions

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Product

Resources

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Titanium allergy or not? "Impurity" of titanium implant materials

Titanium allergy or not? "Impurity" of titanium implant materials