Metallic oxide nanoparticles: state of the art in biogenic syntheses and their mechanisms

Durán, Nélson; Seabra, Amedea B.

doi:10.1007/s00253-012-4118-9

Cited by 109 publications

(60 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, its chemical synthesis is complex and requires extreme conditions. Ionic bismuth is reduced by sodium borohydride and is then oxidized at high temperatures [3]. Biogenic synthesis is an ecofriendly methodology that is widely acceptable.…”

Section: Bismuth Trioxide (Bi2o3) Nanocrystalsmentioning

confidence: 99%

“…The classical methods for obtaining metal oxide nanoparticles are based on chemical and physical techniques that employ hazardous and expensive chemicals with high energy input and a negative effect on the environment [1]. The production of metal oxide nanoparticles via biogenic synthesis has received increasing attention recently because it is a novel process for the development of engineered materials [3]. The biogenic synthesis of nanomaterials by different organisms offers a reliable, low-cost and environment friendly alternative approach compared with classical chemical and/or physical methods [3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

“…These capping agents prevent nanoparticle aggregation and likely play an important role in the stabilization of the nanosystem. The presence of capping agents may improve the biocompatibility of biogenic nanomaterials [3][4][5][6][7][8]. Figure 1 shows a schematic representation of the simplicity of biogenic synthesis of metal oxide nanoparticles along with the advantages and disadvantages of green processes.…”

Section: Introductionmentioning

confidence: 99%

“…The production of metal oxide nanoparticles via biogenic synthesis has received increasing attention recently because it is a novel process for the development of engineered materials [3]. The biogenic synthesis of nanomaterials by different organisms offers a reliable, low-cost and environment friendly alternative approach compared with classical chemical and/or physical methods [3][4][5][6][7][8]. The biogenic synthesis of metallic nanoparticles leads to the formation of capped nanostructures with proteins/biomolecules from the organism during the biosynthesis.…”

Section: Introductionmentioning

confidence: 99%

“…However, the main disadvantages are the limitations related to the scaling up the syntheses processes. In addition, the reproducibility of the biogenic processes needs to be improved, and in most of the cases, the mechanisms of nanoparticle formation are not completely elucidated [3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Nanotoxicology of Metal Oxide Nanoparticles

Seabra

Durán

2015

Metals

Self Cite

188

View full text Add to dashboard Cite

This review discusses recent advances in the synthesis, characterization and toxicity of metal oxide nanoparticles obtained mainly through biogenic (green) processes. The in vitro and in vivo toxicities of these oxides are discussed including a consideration of the factors important for safe use of these nanomaterials. The toxicities of different metal oxide nanoparticles are compared. The importance of biogenic synthesized metal oxide nanoparticles has been increasing in recent years; however, more studies aimed at better characterizing the potent toxicity of these nanoparticles are still necessary for nanosafely considerations and environmental perspectives. In this context, this review aims to inspire new research in the design of green approaches to obtain metal oxide nanoparticles for biomedical and technological applications and to highlight the critical need to fully investigate the nanotoxicity of these particles. OPEN ACCESSMetals 2015, 5 935

show abstract

Section: Bismuth Trioxide (Bi2o3) Nanocrystalsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Nanotoxicology of Metal Oxide Nanoparticles

Seabra

Durán

2015

Metals

Self Cite

188

View full text Add to dashboard Cite

show abstract

Role of Plants in Nanoparticle Synthesis

Kapoor¹,

Rahman²,

Pandit³

et al. 2022

Nanomaterials in Clinical Therapeutics

View full text Add to dashboard Cite

Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

Iqbal

Abbasi

Mahmood

et al. 2019

Applied Organom Chemis

145

View full text Add to dashboard Cite

In the present report, Nickel oxide nanoparticles (NiONPs) were synthesized using Rhamnus virgata (Roxb.) (Family: Rhamnaceae) as a potential stabilizing, reducing and chelating agent. The formation, morphology, structure and other physicochemical properties of resulting NiONPs were characterized by Ultra violet spectroscopy, X-ray diffraction (XRD), Fourier Transform Infrared analysis (FTIR), Scanning electron microscopy (SEM), Energy-dispersivespectroscopy (EDS), Transmission electron microscopy (TEM), Raman spectroscopy and dynamic light scattering (DLS). Detailed in vitro biological activities revealed significant therapeutic potential for NiONPs. The antimicrobial efficacy of biogenic NiONPs was demonstrated against five different gram positive and gram negative bacterial strains. Klebsiella pneumoniae and Pseudomonas aeruginosa (MIC: 125 μg/mL) were found to be the least susceptible and Bacillus subtilis (MIC: 31.25 μg/mL) was found to be the most susceptible strain to NiONPs. Biogenic NiONPs were reported to be highly potent against HepG2 cells (IC 50 : 29.68 μg/ml). Moderate antileishmanial activity against Leishmania tropica (KMH 23 ) promastigotes (IC 50 : 10.62 μg/ml) and amastigotes (IC 50 : 27.58 μg/ml) cultures are reported. The cytotoxic activity was studied using brine shrimps and their IC 50 value was recorded as 43.73 μg/ml. For toxicological assessment, NiONPs were found compatible towards human RBCs (IC 50 : > 200 μg/ml) and macrophages (IC 50 : > 200 μg/ml), deeming particles safe for various applications in nanomedicines. Moderate antioxidant activities: total antioxidant capacity (TAC) (51.43%), 2,2-diphenyl-1-picrylhydrazyl (DPPH) activity (70.36%) and total reducing power (TRP) (45%) are reported for NiONPs. In addition, protein kinase and alpha amylase inhibition assays were also performed. Our results concluded that Rhamnus virgata synthesized NiONPs could find important biomedical applications with low cytotoxicity to normal cells.

show abstract

Metallic oxide nanoparticles: state of the art in biogenic syntheses and their mechanisms

Cited by 109 publications

References 46 publications

Nanotoxicology of Metal Oxide Nanoparticles

Nanotoxicology of Metal Oxide Nanoparticles

Role of Plants in Nanoparticle Synthesis

Green synthesis and characterizations of Nickel oxide nanoparticles using leaf extract of Rhamnus virgata and their potential biological applications

Contact Info

Product

Resources

About