Metallodendrimers and Dendrimer Nanocomposites

Tang, Yi Hsuan; Huang, Adela Ya Ting; Chen, Po‐Yu; Chen, Hui Ting; Kao, Ching Huei

doi:10.2174/138161211797052367

Cited by 28 publications

(9 citation statements)

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“…A new branch of the dendrimer studies deals with metallodendrimers having unique biological and biomedical activities. The incorporation of metal ions into the dendrimer structure opens interesting prospects for dendrimer chemistry and facilitates their enhanced biological activity [7,8]. Therefore, lately, the application of such compounds in medical chemistry as a new class of metal-containing biomolecules-has expanded significantly.…”

Section: Introductionmentioning

confidence: 99%

Surface Functionalization of Cotton Fabric with Fluorescent Dendrimers, Spectral Characterization, Cytotoxicity, Antimicrobial and Antitumor Activity

et al. 2019

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Poly(propylenimine) dendrimers from first and third generations modified with 1,8-naphthalimide units and their Zn(II) complexes have been investigated by absorption and fluorescence spectroscopy. These dendrimers have been deposited on a cotton cloth by the extraction method, producing yellow-colored textile materials. They have been characterized by defining their color coordinates L*a*b*, XYZ and xy. The antimicrobial activity of dendrimers has been investigated in vitro against model gram-positive and gram-negative bacteria and yeasts. Being deposited onto the surface of cotton fabric, the studied dendrimers reduced bacterial growth and prevented the formation of bacterial biofilm. Anticancer and cytotoxicity activities have also been performed against HeLa and Lep-3 human tumor cell lines as model systems.

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Section: Introductionmentioning

confidence: 99%

Surface Functionalization of Cotton Fabric with Fluorescent Dendrimers, Spectral Characterization, Cytotoxicity, Antimicrobial and Antitumor Activity

et al. 2019

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“…Some biomimetic nanomaterials, such as metal oxides (Piro and Reisberg, 2017;Nikolova and Chavali, 2020), metal hydroxides (Sun et al, 2019) metallodendrimers (Tang et al, 2011), and polymers (Zhao et al, 2018;Regan et al, 2019) have also been applied as biomimetic nanomaterials for disease diagnosis; however, these nanomaterials are not discussed in this review.…”

Section: Protein-based Nanomaterialsmentioning

confidence: 99%

Advanced Biomimetic Nanomaterials for Non-invasive Disease Diagnosis

et al. 2021

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In modern society, the incidence of cancer, inflammatory diseases, nervous system diseases, metabolic diseases, and cardiovascular diseases is on the rise. These diseases not only cause physical and mental suffering for patients, but also place an enormous burden on society. Early, non-invasive diagnosis of these diseases can reduce the physical and mental pain of patients and social stress. There is an urgent need for advanced materials and methods for non-invasive disease marker detection, large-scale disease screening, and early diagnosis. Biomimetic medical materials are synthetic materials designed to be biocompatible or biodegradable, then developed for use in the medical industry. In recent years, with the development of nanotechnology, a variety of biomimetic medical materials with advanced properties have been introduced. Biomimetic nanomaterials have made great progress in biosensing, bioimaging, and other fields. The latest advance of biomimetic nanomaterials in disease diagnosis has attracted tremendous interest. However, the application of biomimetic nanomaterials in disease diagnosis has not been reviewed. This review particularly focuses on the potential of biomimetic nanomaterials in non-invasive disease marker detection and disease diagnosis. The first part focuses on the properties and characteristics of different kinds of advanced biomimetic nanomaterials. In the second part, the recent cutting-edge methods using biosensors and bioimaging based on biomimetic nanomaterials for non-invasive disease diagnosis are reviewed. In addition, the existing problems and future development of biomimetic nanomaterials is briefly described in the third part. The application of biomimetic nanomaterials would provide a novel and promising diagnostic method for non-invasive disease marker detection, large-scale clinical screening, and diagnosis, promoting the exploitation of devices with better detection performance and the development of global clinical public health.

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“…In case of their prone-to-agglomerate in solution, stabilization of NPs is of great deal. Among various stabilizers such as surfactants (11), ligands, micelles and polymers (12,13), dendrimers are promising templates to synthesize numerous transition metal NPs such as Ag (14)(15)(16), Au (14,17), Cu (18,19), Ni (20), and Ru (21) with well-regulated size, position, and composition depending on their three-dimensional, monodisperse, unique architectures preventing them from nanoparticle growth, assembly, aggregation, and damage (22,23). Thus, the size and shape of the resulting dendrimer nanocomposites (DNCs) or dendrimerencapsulated metal nanoparticles (DENs), can remain steady so that a constant desired activity can be reached.…”

Section: Introductionmentioning

confidence: 99%

“…In recent years, DNCs have been intensively prepared and characterized by using commercially available ethylene diamine core poly(amido amine) (PAMAM) cored dendrimers, and their catalytic properties were investigated (22). Results of these studies revealed that generation number and surface functional group has a crucial role on effect on the catalytic activity of DNCs.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Jeffamine Core PAMAM Dendrimer-Silver Nanocomposites (Ag JCPDNCs) and Their Evaluation in The Reduction of 4-Nitrophenol

Gürbüz¹,

Ertürk²

2018

Journal of the Turkish Chemical Society Section A: Chemistry

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This paper presents the synthesis, characterization, and catalytic evaluation of Jeffamine core PAMAM dendrimer-silver nanocomposites (Ag JCPDNCs). Generation-4 polymeric Jeffamine cored PAMAM dendrimer (JCPD or P4.NH2) was used as the stabilizing and templating agent for the synthesis of Ag-JCPDNCs. Characterization of the synthesized Ag JCPDNC was performed by UV-visible (UV-Vis) spectroscopy and high resolution transmission electron microscopy (HRTEM). The catalytic activity of dendrimer nanocomposite (DNC) was assessed on the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AMP) in the presence of sodium borohydride (NaBH4) as reducing agent by monitoring the conversion at λ = 400 nm. The prepared Ag JCPDNCs displayed a good catalytic activity (K = 0.12 x 10-2 s-1) for the model reduction reaction of 4-NP with the particle size distribution of 4.72 ± 0.81 nm, which offer a mixed type (interior and exterior) of DNC formation. The Ag JCPDNCs can be a valid complete alternative to their existing candidates in the literature with their different polymeric organics components and be great potential for the future studies as new materials.

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Metallodendrimers and Dendrimer Nanocomposites

Cited by 28 publications

References 0 publications

Surface Functionalization of Cotton Fabric with Fluorescent Dendrimers, Spectral Characterization, Cytotoxicity, Antimicrobial and Antitumor Activity

Surface Functionalization of Cotton Fabric with Fluorescent Dendrimers, Spectral Characterization, Cytotoxicity, Antimicrobial and Antitumor Activity

Advanced Biomimetic Nanomaterials for Non-invasive Disease Diagnosis

Synthesis and Characterization of Jeffamine Core PAMAM Dendrimer-Silver Nanocomposites (Ag JCPDNCs) and Their Evaluation in The Reduction of 4-Nitrophenol

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