Metallophthalocyanines as Catalysts in Aerobic Oxidation

Abstract

The first remarkable property associated to metallophthalocyanines (MPcs) was their chemical “inertness”, which made and make them very attractive as stable and durable industrial dyes. Nevertheless, their rich redox chemistry was also explored in the last decades, making available a solid and detailed knowledge background for further studies on the suitability of MPcs as redox catalysts. An overlook of MPcs and their catalytic activity with dioxygen as oxidants will be discussed here with a special emphasis on the last decade. The mini-review begins with a short introduction to phthalocyanines, from their structure to their main features, going then through the redox chemistry of metallophthalocyanines and their catalytic activity in aerobic oxidation reactions. The most significant systems described in the literature comprise the oxidation of organosulfur compounds such as thiols and thiophenes, the functionalization of alkyl arenes, alcohols, olefins, among other substrates.

Doped Graphene To Mimic the Bacterial NADH Oxidase for One-Step NAD+ Supplementation in Mammals

“…An FeNGR material with single-metal-atom sites (Fe–N x moieties) was shown to selectively catalyze the oxidation of a broad range of aromatic hydrocarbons into their corresponding ketones, and a CoNGR material with Co–N x sites was reported to selectively catalyze the one-hydrogen abstraction from propane, resulting in propene . This ability of MNGR materials with M–N x sites covalently embedded in graphene sheets to catalytically activate C–H bonds is in line with a similar ability reported for non-pyrolyzed metal-phthalocyanines comprising a well-defined M–N 4 center. , Metal-phthalocyanines are, however, less robust than MNGR single-atom catalysts, and their synthesis is more complex. Due to the reported activity of MNGR to activate C–H bonds selectively and efficiently, we hypothesized that they can be potential catalysts to mimic the activity of NOX for the catalytic elevation of NAD + in mammalian cells.…”

The regioselective Wacker oxidation of internal allylamines: synthesis of functionalized and challenging β-amino ketones

“…Organic & Biomolecular Chemistry involves the participation of an electron transfer mediator (ETM) to improve the efficiency of the oxygen oxidation of hydroquinone and the subsequent oxidation of Pd(0) species. 56 We decided to focus on two common ETM agents, Fe( pc) ( pc: phthalocyanine) 43,57 and Co(salophen), 58,59 and evaluate their efficiency for the Wacker oxidation of allylamines.…”

Synthesis, Characterization, and Physicochemical Studies Of Orientation‐Controlled Multi‐Arm PEG Zn(II)/Mg(II) (Aza)Phthalocyanines

“…Polyvalent hydrophobic substances such as calix [4]arenes, [1] resorcin [4]arenes, [2] rigid bowl shaped "cavitands", [3] pill [5]arenes, [4] fullerene, [5] porphyrins, [6] and (aza)phthalocyanines (Pcs/AzaPcs) [7] have unique applications, however studies aimed at gaining a better understanding of their unique bulk and solution properties are hindered by insolubility and aggregation issues. [8] aggregation issues [8] (Figure 1). In particular, Pcs/AzaPcs have interesting solution and interfacial properties, and they applied in many advance areas, [9] especially those related to biology and medicine.…”