Metamorphopsia and Morphological Changes in the Macula after Scleral Buckling Surgery for Macula-Off Rhegmatogenous Retinal Detachment

Abstract

Purpose. To observe the changes in metamorphopsia after scleral buckling (SB) surgery for macula-off rhegmatogenous retinal detachment (RRD) and its association with morphological changes in the macula. Methods. This prospective study included 20 eyes of 20 patients. Before surgery and 1, 3, 6, and 12 months after surgery, metamorphopsia measured by M-charts and best-corrected visual acuity (BCVA) and macular microstructures assessed using optical coherence tomography were recorded. Results. Both the vertical and horizontal M-scores improved significantly after SB surgery. BCVA also improved gradually. The mean M-score in the eyes with a continuous external limiting membrane (ELM) was smaller than that in the eyes with a disrupted ELM ( P = 0.008 ). Preoperative and postoperative BCVA did not correlate with the mean M-score at any time point. The other studied parameters, namely, the duration of RRD, the height of retinal detachment, central foveal thickness, inner nuclear layer thickness, and continuation of the ellipsoid zone, were also not relevant. Conclusions. The continuation of the ELM may be a critical factor in determining the severity of metamorphopsia after SB surgery for macula-off RRD.

Structural and Functional Analysis of Multiple Subretinal Fluid Blebs after Successful Surgery for Rhegmatogenous Retinal Detachment

“…Metamorphopsia was evaluated using M-charts (Inami, Tokyo, Japan); the quantifying procedure was the same as used by Nowomiejska et al [17] and Xu et al [7]. Patients within 30 cm of the charts were asked to identify whether vertical and horizontal dotted lines appeared straight.…”

“…Unfortunately, successful retinal reattachment does not necessarily lead to satisfactory recovery of visual function [4][5][6]. Many patients remain distressed by low best-corrected visual acuity (BCVA) and metamorphopsia, although retinal reattachment was successful [7,8].…”

Recombinant Plasminogen Activator Modified Nanoparticles for Targeting Thrombolysis in Branch Retinal Vein Occlusion

“…Therefore, there is an urgent need for the thrombolytic treatment institutions of retinal vein branch submembrane vein vascular occlusion to continuously improve its rtPA thrombolytic biological resource utilization, thrombolytic therapy effect and drug safety. The charging status of rtPA is shown in Table 1: The summary of the overall construction solution of the complete nano-ring-opening drug delivery system is as follows: First, the block ring-opening drugdelivery polymerization method is used to separately cap the methoxy lactone-terminated ring-opening polyethylene glycol (MPEG) or the carboxyl lactoneterminated ring-opening Polyethylene glycol (COOH-PEG) reacts with ε-caprolactone to synthesize a block drug delivery copolymer containing PEG-PCL diol (8)(9). The above-mentioned block copolymers are mixed in a certain amount of ratio, and complete nanometer particles are made by a single polymerization emulsification/solvent polymerization evaporation method; then each nanometer drug delivery particle is made by the polymerization method using EDC/NHS Its surface carboxyl group (COOH) is activated, and rtrtPA emulsification reaction merges to form a covalent bond connection to obtain tissue-type plasmin activator-modified nanoparticles (rtPA-NP).…”

Correlation between retinal sensitivity and foveal microstructure after successful surgery for rhegmatogenous retinal detachment

“…The incidence of ERM formation after RRD ranges from 4.6-28% (11)(12)(13)(14). Disruption of the ELM and EZ can re ect the overall structure of photoreceptor cells and affect the results of the best-corrected visual acuity (BCVA) and metamorphopsia assessment (15)(16)(17). The recovery of the ELM and EZ was signi cantly correlated with improved BCVA (6).…”