Metaphyseal and diaphyseal chondroblastomas

Abstract

Pure metaphyseal and/or diaphyseal CB are exceedingly rare. A presumptive diagnosis may be considered in the appropriate age group in the presence of chondroid matrix, perilesional edema, periosteal reaction, and marginal sclerosis. Regardless of all the diagnostic possibilities, biopsy may still be required. However, knowledge of this entity will help make the final diagnosis and guide the correct treatment.

Chondroblastoma of Bone in the Extremities

“…Although the tumor may secondarily involve the metaphysis and even the diaphysis (probably by extension across the physis), primary metaphyseal or diaphyseal occurrences of this disease without epiphyseal or apophyseal involvement are exceptionally rare 14 .…”

A fatal case of pure metaphyseal chondroblastoma

“…In contrast one study19 has been shown that non-epiphysial CBs were associated with a lower risk of recurrence. The reason may be related to this fact that non-epiphysial lesions are away from the epiphysis, so a more aggressive surgical approach can be taken.…”

Surface-based chondroblastoma of the tibia: a unique presentation

“…Although one case in this latter tabulation is listed as being diaphyseal, this is in error, as the report by Dahlin and Ivins [1] that is referenced did not contain any examples of diaphyseal CB. In their report, however, Maheshwari et al provide a separate listing of 51 cases of extra-epiphyseal CBs in small, tubular, and flat bones that had been reported from 1951 to 2009, 6 of which were purely diaphyseal [15].…”

“…The remainders were described as Bcortical,â nd one as a Bsurface^lesion, but no details of these cases are given [6]. All of the metaphyseal-and diaphyseal-based CBs described by Maheshwari et al were also intramedullary [15].…”

“…Among 126 tubular bone CBs from The Netherlands Bone Tumor Registry, 114 (90 %) were epiphyseal or metaepiphyseal, 5 (4 %) were metaphyseal, 4 (3 %) were metadiaphyseal, and only 1 (0.8 %) was diaphyseal [5]. Maheshwari et al [15] reviewed 390 cases of CB in the database of the Armed Forces Institute of Pathology (AFIP) and Washington Hospital Center and found only 7 (1.8 %) that were purely metaphyseal (2 cases), metadiaphyseal (4 cases), or diaphyseal (1 case). In the same publication, Maheshwari et al also reviewed 10 previous series of long bone CBs totaling 690 cases, with only 2.2 % identified as purely metaphyseal.…”