Metascience in Bioinformation

Khakshooy, Allen; Bach, Quyen; Kasar, Vandan; Chiappelli, Francesco

doi:10.6026/97320630016004

Cited by 5 publications

(7 citation statements)

References 5 publications

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“…EBHC is a product of metascience, the hypothesis-driven process of systematic inquiry of the best available evidence, and its optimal application in practice [33,34]…”

Section: Evidence-based Healthcare (Ebhc)mentioning

confidence: 99%

“…The best available evidence is derived systematically from the stringent, hypothesis-driven process of research synthesis, and is reported as systematic reviews [33][34][35][36][37][38][39][40][41][42]. Across any field of inquiry, research evidence usually results from excellent science, but it may also emerge from scientific reports that suffer from serious methodologically flaws and biases.…”

Section: Evidence-based Researchmentioning

confidence: 99%

“…Research synthesis systematically sifts out the scientific evidence that is corrupt and that should not be utilized in evidence-based practice. It pulls together the consistent and coherent high-quality science; and it generates a qualitative and quantitative (i.e., meta-analysis) consensus of the best evidence for translation and integration into new and improved evidence-based practice [1][2][3][33][34][35][36][37][38][39][40][41][42][43][44][45]. In brief, EBHC in general, and evidence-based research in particular is effectiveness-focused because risk(cost)/benefit concerns must always remain primary.…”

Section: Evidence-based Researchmentioning

confidence: 99%

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Untitled

2023

Bioinformation

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The author's state that they adhere with COPE guidelines on publishing ethics as described elsewhere at https://publicationethics.org/. The authors also undertake that they are not associated with any other third party (governmental or non-governmental agencies) linking with any form of unethical issues connecting to this publication. The authors also declare that they are not withholding any information that is misleading to the publisher in regard to this article.

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“…EBHC is a product of metascience, the hypothesis-driven process of systematic inquiry of the best available evidence, and its optimal application in practice [33,34]…”

Section: Evidence-based Healthcare (Ebhc)mentioning

confidence: 99%

Section: Evidence-based Researchmentioning

confidence: 99%

Section: Evidence-based Researchmentioning

confidence: 99%

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Untitled

2023

Bioinformation

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“…Rigorous evidence-based analysis should seek to eliminate both misinformation (inaccurate information created by honest mistake) and disinformation (inaccurate information used for intentional deceit). 118 The profession should adopt a stringent peer-review process to eradicate poor science, and to abolish the publication of low-quality articles and predatory journals, in order to rebuild lost confidence within the public and the profession. 119…”

Section: Clinical Recommendations and Future Directionsmentioning

confidence: 99%

“…Clinical guidelines should be developed from sound principles of evidence‐based dentistry, and clinicians should be better trained to develop critical analytical skills, 117 which call for improved curriculum design in dental schools and continuing professional development events. Rigorous evidence‐based analysis should seek to eliminate both misinformation (inaccurate information created by honest mistake) and disinformation (inaccurate information used for intentional deceit) 118 . The profession should adopt a stringent peer‐review process to eradicate poor science, and to abolish the publication of low‐quality articles and predatory journals, in order to rebuild lost confidence within the public and the profession 119…”

Section: Clinical Recommendations and Future Directionsmentioning

confidence: 99%

Opening up on airways: the purported effect of nasorespiratory obstruction on dentofacial growth

Cheung

Dreyer

Ranjitkar

2021

Australian Dental Journal

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Nasorespiratory obstruction has been purported to influence dentofacial growth adversely. This has sparked considerable debate for decades with a resurgence in interest in 'airway friendly orthodontics' among both general and specialist dental practitioners. This critical review aims to evaluate the current literature relating to two questions: does nasorespiratory obstruction alter dentofacial growth, and does early intervention targeted at alleviating nasorespiratory obstruction improve dentofacial growth? The strength of association between nasorespiratory obstruction, mouth breathing and a long face is weak. The common methodological flaws in research include unblinded and cross-sectional study designs, a lack of adequate controls, inadequate follow-up, subjective assessments and inadequate statistical power. Vertical dentofacial growth has a strong genetic influence, which implies a relatively minor contribution of environmental factors including airway obstruction. The current evidence does not support recommending procedures, such as adenotonsillectomy and maxillary expansion, with the singular aim of negating a hyperdivergent (vertical) dentofacial growth pattern. In light of low-quality evidence, both the World Health Organization guidelines and ethical principles dictate that greater emphasis is placed on avoiding harm and wastage of resources over alternative options. These findings call for quality improvement in undergraduate and postgraduate curricula and continuing professional development for health professionals.

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