Métastases au niveau des seins de tumeurs extramammaires. Caractéristiques cliniques, radiologiques et démarche diagnostique. À propos de deux cas et revue de la littérature

Magri, K.; Demoulin, G.; Millon, G; Duvert, Bernard

doi:10.1016/j.jgyn.2007.04.011

Cited by 7 publications

(1 citation statement)

References 16 publications

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“…Breast metastases from extragenital cancers are very rare, occurring in just 0.5–6% of patients with breast cancer 1. In a study of 6668 oncology patients, Surov et al .…”

Section: Discussionmentioning

confidence: 99%

ALK rearrangement in lung adenocarcinoma with concurrent cervix and breast metastases: A case report

Chuang

Chen

et al. 2018

Thoracic Cancer

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Distant metastases of pulmonary adenocarcinoma are regularly observed in the bones, brain, adrenal gland, and liver, but rarely in the breast or cervix. In this report, we describe a novel case of concurrent cervix and breast metastases from lung adenocarcinoma, with ALK rearrangements that were strongly consistent between the primary and metastatic cancers. A 44‐year‐old Chinese woman with a chief complaint of abdominal discomfort was referred to our hospital. Based on diagnostic imaging, pathology, immunohistochemistry, and next‐generation sequencing, the patient was diagnosed with lung adenocarcinoma with breast and cervical metastases, and ALK rearrangements were found in all three lesions. The patient was prescribed crizotinib as first‐line treatment, which showed a steady reduction of the lung lesion. To our knowledge, this is the first report of concurrent breast and cervical metastases from lung adenocarcinoma. We conclude that physicians should consider that metastases may invade the breast and cervix uteri when making a diagnosis.

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“…Breast metastases from extragenital cancers are very rare, occurring in just 0.5–6% of patients with breast cancer 1. In a study of 6668 oncology patients, Surov et al .…”

Section: Discussionmentioning

confidence: 99%