Metastasis of cutaneous squamous cell carcinoma to the stomach: a rare entity

Abstract

Metastatic spread of cutaneous squamous cell carcinoma (cSCC) to the gastrointestinal tract is a rare entity. A 63-year-old woman with a history of poorly controlled HIV and a recurrent cSCC on the right temple presented with functional decline, ascites and shortness of breath. A CT scan showed widespread metastatic malignancy involving lung, pleura, heart, stomach, liver, retroperitoneum and soft-tissue. In the case presented here, an upper endoscopy revealed a submucosal lesion in the stomach. Biopsies described the lesion as a poorly differentiated SCC. Comprehensive genomic profiling yielded striking molecular similarities between the gastric tumour and the patient’s prior cSCC. It confirmed the origin of the disease and excluded spread from an occult primary. This case adds to the limited literature on gastrointestinal metastases of cSCC and serves as a reminder that non-AIDS-defining cancers are on the rise in the HIV-population.

64-Slice Spiral Computerized Tomography under Algebraic Reconstruction Algorithm in the Surgical Treatment of Acquired Immune Deficiency Syndrome Complicated with Gastric Cancer

“…However, as there are a large number of organs in the human body, the density difference among the organs is small, and the contrast is poor, the obtained original CT images often have a lot of noise and artifacts with a poor quality, which affects the judgment of the radiologist. us, the original images need to be enhanced with the help of artificial intelligence algorithms [14][15][16]. e algebraic reconstruction technology (ART) is to reconstruct the image by solving the system of linear equations.…”