Metastasis of Prostate Adenocarcinoma in the Mandible: Rare Occurrence in Maxillary Bones

Abstract

Therefore, ultrasound could be used as a supplemental sign to differential diagnose.Surgical excision is considered to be the best approach for the primary treatment of lymphangiomas, but the postsurgical recurrence rate of CLC is high. 1 Hence, a precise determination of lesion margin would be helpful to define an appropriate safety margin for surgery. 11 Ultrasound has been confirmed to have excellent correlation with the histologic thickness of malignant cutaneous tumors 12 and the present case suggests the same for CLC. The lesion showed hyperechoic characteristics combined with high vascularity and low-speed blood flow. Thanks to the precise evaluation of lesion margin by preoperative ultrasound, including color Doppler and pulse wave Doppler, repeated pre-and intraoperative biopsies were minimized. It could also prevent recurrences.It is well known that craniofacial area is one of the most common sites of CLC. 13 At this area, the skin and subcutaneous tissue are both thin and vulnerable to stretch. So, skin tension of this area would be much more enlarged after the surgery. 14 Too much tension after surgery maybe influence local sensation and functions of nearby sensory organs such as mouth and eyes. To avoid that, we use ultrasound for precise presurgical assessment to minimize the resection area. We think this is also the value of ultrasound assessment for craniofacial CLC preoperational.In conclusion, ultrasound (especially color Doppler and pulse wave Doppler ultrasound) is a versatile non-invasive tool that can help the in diagnosis of CLC. It could help determine the exact depth of the lesion and may help prevent recurrences, but this will have to be determined in future studies.

Finding the Way Back Home: Report of 2 Cases of Oral Metastasis

“…Metastatic lesions in the oral cavity are a rarity and comprise only 1-1.5% of all oral malignant tumors. The primary sites which metastasize to the oral cavity include breast, lung, prostate and kidney in decreasing order of incidence [1]. Since it is a bidirectional phenomenon the metastatic sites most favoured by carcinomas from oral cavity are mainly lung, followed by bone and liver [2].…”

Prostate Cancer With Solitary Bone Metastasis in the Mandible

“…Postoperative pathology results showed the bone lesion as metastatic prostate cancer. Although prostate cancer has a propensity to metastasize to bone, mandible metastasis is rare, and usually present with nonspecific symptoms including jaw pain, swelling, and numb chin syndrome 1–5 . In the reported small number of cases, among the metastatic bone lesions involving the jaws, approximately 5% to 9% were from the prostate gland.…”

“…Although prostate cancer has a propensity to metastasize to bone, mandible metastasis is rare, and usually present with nonspecific symptoms including jaw pain, swelling, and numb chin syndrome. [1][2][3][4][5] In the reported small number of cases, among the metastatic bone lesions involving the jaws, approximately 5% to 9% were from the prostate gland. Solitary bone metastasis from the prostate gland to the mandible is extremely rare, with only few reported cases.…”