Metástasis única en próstata de carcinoma microcítico pulmonar

Yañez, Isabel Gonzalez; López, Margarita Reboredo; López, José Ángel Rodríguez; Santos, María Dolores Arias; Gómez, Jesús García; Mata, Jesús García

doi:10.4321/s0004-06142009000200010

Cited by 1 publication

(3 citation statements)

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“…Over half of lung adenocarcinoma cases are metastatic at diagnosis, commonly involving the liver, adrenal glands, bone, and brain ( 3 ). Lung cancer metastasis to prostate is uncommon, with most cases found incidentally during autopsy ( 1 ).…”

Section: Discussionmentioning

confidence: 99%

“…A PubMed search for cases of prostatic tumors composed of a primary lung cancer revealed 6 cases ( Table 1 ) ( 2 , 3 , 6 – 9 ). Disseminated disease was present in five cases; one report did not specify.…”

Section: Discussionmentioning

confidence: 99%

“…Secondary lung adenocarcinomas typically overexpresses CK7, TTF-1, and AE1/3. TTF-1, in particular, is highly sensitive and specific for primary lung adenocarcinoma and can be reliably used to differentiate between metastatic lung disease and primary prostatic tumors ( 3 ). Prostate adenocarcinoma typically stains positive for NKX3.1 and Napsin-A, although the latter is also frequently positive in lung adenocarcinoma as well.…”

Section: Discussionmentioning

confidence: 99%

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Case report: Isolated oligometastatic disease of the prostate from a primary lung adenocarcinoma

Kamel,

Arjani,

Fedorov

et al. 2024

Front. Oncol.

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Secondary prostate cancer typically occurs from direct seeding of a renal or bladder tumor. Metastasis via hematogenous spread is exceedingly rare and is typically identified incidentally at autopsy. This report describes a 72-year-old male with lung adenocarcinoma initially staged as Stage IA2 who developed oligometastatic disease of the prostate. He was initially treated with radiation therapy and was found to have a hypermetabolic focus in the prostate gland during surveillance PET/CT imaging 6 months following treatment. Subsequent biopsy revealed metastatic lung adenocarcinoma in 6/6 core samples, leading to diagnosis of oligometastatic disease of the prostate. To our knowledge, this is the first report of isolated oligometastatic disease to the prostate from a primary lung adenocarcinoma.

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Section: Discussionmentioning

confidence: 99%