Metastatic Cervical Cancer to the Duodenum: A Learning Point

Abstract

An elderly woman was admitted to the hospital with generalised abdominal pain and bowel obstruction symptoms in a background of renal cell carcinoma and cervical cancer. Investigations showed a degree of gastric outlet obstruction with mild distension of the small bowel loops with no lead point seen and a raised alkaline phosphatase (ALP). Oesophago-gastroduodenoscopy (OGD) showed a stricture at D1/D2; therefore, an enteric stent was inserted. Biopsies showed metastatic cervical cancer. A few cases of metastatic cervical cancer to the duodenum have been reported. Obstructive bowel symptoms in the background of cervical cancer should raise the possibility of metastases in future practice.

Metastases to duodenum in cervical squamous cell carcinoma

“…A comprehensive review of published cases of duodenal metastases from SCC of the cervix in the English literature dating back to 1981 is provided in Table 1. [10][11][12][13][14][15][16] As shown in Table 1, since 1981, even with our report, only 8 cases of duodenal metastasis of cervical cancer have been reported. It is worth noting that the interval time to metastases in our cases was significantly higher than in the others, which may be due to the earlier stage of SCC of the cervix or the suppression of tumor cells by the previous treatment of hysterectomy and radiation therapy.…”

“…Cervical cancer metastasis to the duodenum is rare. A comprehensive review of published cases of duodenal metastases from SCC of the cervix in the English literature dating back to 1981 is provided in Table 1 [10–16] . As shown in Table 1, since 1981, even with our report, only 8 cases of duodenal metastasis of cervical cancer have been reported.…”