Metastatic chondroblastoma. Report of a fatal case with a review of the literature on atypical, aggressive, and malignant chondroblastoma

Kyriakos, Michael; Land, Vita J.; Penning, H. Larry; Parker, Sterling G.

doi:10.1002/1097-0142(19850415)55:8<1770::aid-cncr2820550825>3.0.co;2-q

Cited by 151 publications

(71 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Third, given the exclusion of axial and aggressive tumors, our results of oncological outcome may also represent a best-case estimate of recurrence for patients with chondroblastomas overall. The incidence of metastasis secondary to chondroblastoma is not well defined in our study, but it is believed to occur rarely, in fewer than 1% of patients [12,22]. It is also possible that we did not detect possible metastases given our protocol of imaging post-treatment, which did not include routine chest CT scans at periodic intervals.…”

Section: Discussionmentioning

confidence: 84%

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

Farfalli

Slullitel

Múscolo

et al. 2017

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 84%

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

Farfalli

Slullitel

Múscolo

et al. 2017

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

“…Metastases from chondroblastoma can arise from different primary sites. There is no reported relation of metastasis to previous surgery or nonsurgical treatment, tumour location, or patient age [7,25]. The lung is by far the most common site of distant metastases.…”

Section: Discussionmentioning

confidence: 99%

“…The lung is by far the most common site of distant metastases. Bones different from those of the primary site, soft tissue, the skin, and the liver are also cited [14,25]. The time reported for metastases to manifest clinically ranges from five months to 33 years (average, eight years) from the initial diagnosis of chondroblastoma [25,26].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Mashhour

Rahman

2013

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

Purpose Various methods for the treatment of chondroblastoma of bone have been used including simple curettage, or combined with bone grafting, in addition to the use of adjuvant therapy. However, local recurrence still represents a challenge in the management of this aggressive tumour. This study focuses on evaluating the role of intraregional extended curettage together with the use of adjuvant cryotherapy and autogenous bone grafting in the treatment of benign chondroblastoma of bone aiming to decrease the recurrence rate. Methods All patients with chondroblastoma included in this study underwent intralesional extended curettage, adjuvant cryotherapy using liquid nitrogen, and autogenous iliac crest bone grafting. Follow up for healing of chondroblastoma lesions and detection of any local recurrence was assessed on clinical and radiological bases. The functional outcome was assessed by the Musculoskeletal Tumour Society scoring system. Results The mean follow-up period was 49 months. The average time for bone healing was 7.4 months. Our rate of local recurrence is 7.1 %. Two patients (14.3 %) developed physeal growth arrest. One patient had superficial skin sloughing (7.1 %). None of the cases had pathological fracture. The mean Musculoskeletal Tumour Society functional score was 92.7 %. Conclusion Chondroblastoma is an aggressive benign bone tumour with a high rate of recurrence. The use of high-speed burr combined with adjuvant intralesional cryotherapy and iliac crest autogenous bone grafting is a reliable method of treatment with a low rate of recurrence.

show abstract

“…It has been reported that the overall recurrence rate of benign tumors following curettage is less than 10% [1,2]. However, giant cell tumors or chondroblastomas require more careful management due to their high rate of recurrence [3,4]. Thus, local adjuvants should be considered to decrease the local recurrence rate in these cases.…”

Section: Introductionmentioning

confidence: 99%

Accuracy and limitations of computer-guided curettage of benign bone tumors

Lee

Shim

Jin

et al. 2012

Computer Aided Surgery

View full text Add to dashboard Cite

Adequate curettage of benign bone tumors located close to articular joints or neurovascular tissue is difficult without damaging those tissues. The purpose of this study was to evaluate the adequacy of tumor removal in computer-assisted curettage of benign bone tumors. The study is a prospective case series involving eight patients with benign bone tumors located near an articular joint or major neurovascular tissue. Image-to-patient registration with the navigation system was performed using paired-points methods in conjunction with CT images. A cortical window was created to visualize the tumor cavity. After removal of the gross tumor with sharp curettes, a specially designed burr attached to a navigation probe was used to monitor the location of the burr tip in real time. The high-speed burr extended the bony margin a few millimeters over the cavity wall. The empty cavity was then filled with bone cement. We assessed the accuracy of curettage and articular involvement by comparing pre-and post-operative CT images.In all cases, deeply seated or multi-cystic tumors were sufficiently removed according to the pre-and post-operative fusion CT images. The subchondral bone was punctured when the initial thickness of the subchondral bone was less than 2.5 mm. However, use of the computer-guided burr was safe if the thickness of the subchondral bone was greater than 3 mm.Computer-assisted curettage is a safe and useful method for localizing deeply seated benign bone tumors. However, use of the burr should be avoided when the bone thickness is less than 3 mm to avoid major tissue damage.

show abstract

Metastatic chondroblastoma. Report of a fatal case with a review of the literature on atypical, aggressive, and malignant chondroblastoma

Cited by 151 publications

References 31 publications

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Accuracy and limitations of computer-guided curettage of benign bone tumors

Contact Info

Product

Resources

About