Metastatic clear cell sarcoma of the pancreas: A rare case report

Abstract

BACKGROUND Clear cell sarcoma (CCS) is a rare soft-tissue sarcoma. The most common metastatic sites for CCS are the lungs, bones and brain. CCS is highly invasive and mainly metastasizes to the lung, followed by the bone and brain; however, pancreatic metastasis is relatively rare. CASE SUMMARY We report on a rare case of CCS with pancreatic metastasis in a 47-year-old man. The patient had a relevant medical history 3 years ago, with abdominal pain as the main clinical manifestation. No abnormalities were observed on physical examination and the tumor was found on abdominal computed tomography. Based on the medical history and postoperative pathology, the patient was diagnosed with CCS with pancreatic metastasis. The patient was successfully treated with surgical interventions, including distal pancreatectomy and splenectomy. CONCLUSION This report summarizes the available treatment modalities for CCS and the importance of regular postoperative follow-up for patients with CCS.

Metastatic clear cell sarcoma of the pancreas: A sporadic cancer

“…Because metastatic sarcoma to the pancreas is uncommon and it can be challenging to differentiate between primary and metastatic tumors using radiologic markers, it presents diagnostic and treatment challenges in clinical practice. Solitary lesions are especially difficult and are clinically mistaken as primary tumors of the pancreas in approximately one-third of cases[ 33 ]. The manifestations of metastatic sarcoma to the pancreas are similar to adenocarcinoma and may include abdominal pain, intestinal obstruction, anemia, nausea, and vomiting.…”