Metastatic gastric adenocarcinoma mimicking osteomyelitis of second toe

Kakarala, Gopikrishna; Chatha, Hamid Aizaz; Ferns, Bernard; Ebizie, Anele

doi:10.1016/j.foot.2008.03.004

Cited by 5 publications

(10 citation statements)

References 6 publications

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“…X-ray will identify most of these features, although computed tomography and MRI can further aid diagnosis. [7][8][9] The features of complete destruction without periosteal reaction were present in this case.Metastases to the foot can be confused for benign conditions such as gout, osteoarthritis, superficial soft tissue infection or related to conditions such as rheumatoid arthritis. 3,7 Whilst the prognosis is generally poor for acrometastasis due to disseminated disease at diagnosis, up to 37% of cases have been reported as the first manifestation.…”

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confidence: 49%

Mediastinal air‐fluid level and an uncommon oesophageal condition

Victor

Surendran

Yacob

et al. 2021

ANZ Journal of Surgery

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lesion as osteomyelitis. It was not until amputation of the digit due to its aggressive nature that histology identified neoplasia. Radiographical features of acrometastases can mimic osteomyelitis. However, health professionals must recognise that osteomyelitis presents with a combination of metaphyseal mottling and periosteal reaction, whilst metastasis presents as entire demineralisation of the phalanx without periosteal reaction. X-ray will identify most of these features, although computed tomography and MRI can further aid diagnosis. [7][8][9] The features of complete destruction without periosteal reaction were present in this case.Metastases to the foot can be confused for benign conditions such as gout, osteoarthritis, superficial soft tissue infection or related to conditions such as rheumatoid arthritis. 3,7 Whilst the prognosis is generally poor for acrometastasis due to disseminated disease at diagnosis, up to 37% of cases have been reported as the first manifestation. 6 Moreover, there are a wide variety of neoplasms that have been histologically identified to metastasise to the foot, and at least 31 different primary malignancies have been reported in the literature. 4 Misdiagnosis leads to delays in treatment and inappropriate interventions.Metastases to the foot can be confused for common benign conditions. A thorough clinical assessment and radiographs of the affected area are crucial for accurate diagnosis. Clinicians must remain vigilant, and consider neoplasia early as a differential diagnosis.

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confidence: 49%

Mediastinal air‐fluid level and an uncommon oesophageal condition

Victor

Surendran

Yacob

et al. 2021

ANZ Journal of Surgery

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“…Palliative treatment of bone metastases has always been conservative: radiotherapy, chemotherapy, immunotherapy, targeted therapy, bisphosphonates and analgesics [58]. More recently, minimally invasive techniques, including ethanol ablation, laser ablation, microwave ablation, cryoablation and radiofrequency ablation, have been used for painful Lung cancer 11 [2,[7][8][9][10][11][12][13][14][15][16] Cervical carcinoma 2 [16,17] Endometrial cancer 5 [18][19][20] Prostatic cancer 5 [23][24][25] Breast cancer 3 [3,28,29] Intestinal tumor 7 [30,31] Bladder cancer 2 [3,34] Kidney cancer 7 [35][36][37][38][39] Gastric adenocarcinoma 2 [42,43] Table 2 Malignant tumors metastasized to the foot skeleton…”

Section: Discussionmentioning

confidence: 99%

“…Others Urothelial carcinoma of the urete [44], Submandibular gland carcinoma [45], Hypopharyngeal epidermoid carcinoma [9], Melanoma [46], Multiple myeloma [3],Humeral osteogenic sarcoma [30], Non-Hodgkin Lymphoma [47], Nasopharyngeal carcinoma [48], Esophagus carcinoma [49], Hypernephroma [30] [3,8,16,18,22,24,26,27,29,32,38,42] Metatarsals 14 [2, 7, 10-12, 19, 31-35, 39, 46, 49] Phalanges 13 [9,17,20,21,28,36,40,41,43,45,47,48,53] Talus 1 [13] Cuboid 4 [25,32,33,47] Navicular bones 3 [14,23,33] Cuneiform bones 4 [ 2,15,33,37] bone lesions [59]…”

Section: Discussionmentioning

confidence: 99%

Metatarsal metastasis from clear cell renal cell carcinoma: a case report and literature review

Han

Zhang

et al. 2020

BMC Urol

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Background: Bone metastasis is known to occur in some patients with cancer, usually in the spine, pelvis or ribs, and less than 0.01% of patients have metastases in the foot bone, so metatarsal metastasis is quite rare. The initial symptoms of osseous metastases are swelling, pain, or both. Case presentation: We report a 68-year-old man with solitary metatarsal metastasis 26 months after a diagnosis of renal clear cell carcinoma. The patient suffered intermittent swelling of his right foot and pain for one year due to trauma and was not treated. The doctor attributed the symptoms to trauma, administering massage therapy and a plaster cast to the patient at the local clinic. After reviewing the medical records, we found that this patient had a history of clear cell renal cell carcinoma. The patient underwent radiological examination and open biopsy of the first metatarsal bone of the right foot. These findings confirmed that the patient had a metatarsal metastasis from clear cell renal cell carcinoma. The patient subsequently underwent right foot amputation. No local recurrence or distant metastasis was found after a 6-month follow-up. Conclusion: Clinicians should be aware of a history of renal cell carcinoma (RCC) and fully understand the patient's past medical history. When treating patients with clear cell renal cell carcinoma who have unresolving bony pain or swelling, clinicians should always keep in mind the possibility of bone metastasis of RCC.

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“…Options for treatment include local curettage with either bone grafting or cementation or below knee amputation (13). In some reported cases, surgical resection of the solitary bone lesion was accompanied with an acceptable survival (10, 14, 15). Our patient underwent surgical resection of the lesion together with radiotherapy and chemotherapy.…”

Section: Discussionmentioning

confidence: 99%