Metastatic infection secondary to genitourinary tract sepsis

Siroky, Mike B.; Moylan, Robert A; Austen, George; Olsson, Carl A.

doi:10.1016/0002-9343(76)90372-7

Cited by 44 publications

(14 citation statements)

References 91 publications

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“…13 Infectious organisms within the genitourinary or gastrointestinal systems can spread to the spine through epidural veins. 59 This type of transvenous inoculation is believed to be the major mechanism in the development of rare infections involving the posterior elements of the spine. 2,64 Moreover, infection within the disc space or adjacent VBs can be transmitted to the epidural space through the epidural venous plexus to form an epidural abscess.…”

Section: Pathogenesismentioning

confidence: 99%

Diagnosis and management of adult pyogenic osteomyelitis of the cervical spine

Acosta

Chin

Quiñones‐Hinojosa³

et al. 2004

FOC

118

119

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Establishing the diagnosis of cervical osteomyelitis in a timely fashion is critical to prevent catastrophic neurological injury. In the modern imaging era, magnetic resonance imaging in particular has facilitated the diagnosis of cervical osteomyelitis, even before the onset of neurological signs or symptoms. Nevertheless, despite advancements in diagnosis, disagreement remains regarding appropriate surgical treatment. The role of instrumentation and type of graft material after cervical decompression remain controversial. The authors describe the epidemiological features, pathogenesis, and diagnostic evaluation, and the surgical and nonsurgical interventions that can be used to treat osteomyelitis of the cervical spine. They also review the current debate about the role of instrumentation in preventing spinal deformity after surgical decompression for cervical osteomyelitis. Based on this review, the authors conclude that nonsurgical therapy is appropriate if neurological signs or symptoms, instability, deformity, or spinal cord compression are absent. Surgical decompression, debridement, stabilization, and deformity correction are the goals once the decision to perform surgery has been made. The roles of autogenous graft, instrumentation, and allograft have not been clearly delineated with Class I data, but the authors believe that spinal stability and decompression override creating an environment that can be completely sterilized by antibiotic drugs.

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Section: Pathogenesismentioning

confidence: 99%

Diagnosis and management of adult pyogenic osteomyelitis of the cervical spine

Acosta

Chin

Quiñones‐Hinojosa³

et al. 2004

FOC

118

119

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“…Because the patient self‐catheterized several times daily, we suspect that the urinary tract provided the bacterial source. For more than 50 years, it has been recognized that genitourinary tract infections, especially after instrumentation of the tract, can metastasize to the spine [8–13]. The pelvic venous plexus has been postulated as a potential route of spread [14–16].…”

Section: Discussionmentioning

confidence: 99%

Septic Facet Joint Arthritis after a Corticosteroid Facet Injection

2006

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Lumbar facet joint injections are commonly employed in the treatment of low back pain and are considered to be relatively safe with few known complications. We report the case of septic facet arthritis following a periarticular facet injection in a patient with recurrent urinary tract infections. The literature is reviewed to identify epidemiological and clinical features of patients in whom septic facet arthritis developed after lumbar facet injection. The diagnosis of iatrogenic septic facet arthritis is often delayed because neurologic and constitutional signs and symptoms develop slowly. Serologic nonspecific markers of infection and appropriate imaging studies may be more sensitive for the early diagnosis of septic facet arthritis. Recalcitrant or worsening back pain after facet injections should prompt an investigation to rule out infectious causes.

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“…More serious infective complications are possible; clinical septicaemia developed in one patient in this series. Delayed metastatic infections, such as endocarditis, are rare but disastrous complications of urological manipulations; in one series (Siroky et al, 1976), urethral dilatation was responsible for 15% of distant infections and Escherichia coli and Staphylococcus aureus were the most common pathogens.…”

Section: Discussionmentioning

confidence: 99%

Oral Ciprofloxacin as Prophylaxis for Optical Urethrotomy

Murdoch

Badenoch

1987

British Journal of Urology

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It is known that urethral strictures predispose to bacteriuria. We studied a series of patients undergoing optical urethrotomy to see if antibiotic prophylaxis was justified. Twenty-three patients were randomised to receive either no prophylaxis or a short peri-operative course of oral ciprofloxacin. Two patients with sterile pre-operative urine and two patients with pre-operative bacteriuria given no prophylaxis had post-operative bacteriuria, whereas all patients given ciprofloxacin had sterile urine after operation. Antibiotic prophylaxis may be indicated in patients undergoing optical urethrotomy.

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Metastatic infection secondary to genitourinary tract sepsis

Cited by 44 publications

References 91 publications

Diagnosis and management of adult pyogenic osteomyelitis of the cervical spine

Diagnosis and management of adult pyogenic osteomyelitis of the cervical spine

Septic Facet Joint Arthritis after a Corticosteroid Facet Injection

Oral Ciprofloxacin as Prophylaxis for Optical Urethrotomy

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