Metastatic Lung Carcinoma Involving the Periodontium. Report of a Case

Abstract

A case of metastatic bronchogenic carcinoma to the gingiva in a 47-year-old male is reported. The gingival lesion developed as a quickly growing mass and appeared 2 months after surgical excision and radiotherapy of the lung carcinoma were completed. The gingival tumor was histopathologically diagnosed as a poorly differentiated squamous carcinoma. Comparative cytologic studies showed similarities between the gingival metastasis and the previous lung cancer.

Gingival Metastasis From a Prostate Adenocarcinoma: Report of a Case

“…The tumors most frequently found are adenocarcinomas, epidermoid carcinomas, seminomas, sarcomas, undifferentiated carcinomas, renal carcinomas, angiosarcomas, Merkel cell carcinomas, and melanomas. 8,9,12,[17][18][19] The gingival metastases must be removed since they cause discomfort, pain, and bleeding. 15 The main symptoms are bleeding and the presence of an ulcerated and rapidly growing mass.…”

“…5,8,10 The lesion appeared as an ulceration in approximately only 10% of the cases. 3 A biopsy is mandatory to confirm the diagnosis, 3,9 except in patients with obvious widespread malignancy. 5 Metastatic tumors affecting the periodontium arise from lung (35.5%), kidney (16%), and skin (15%) in males and breast (24%), genitals (17%), lung (12%), bone (10.3%), and kidney (10.3%) in females.…”

“…3 Although oral metastases are not common, periodontists should be aware of them 8 and determine appropriate management of local and systemic oncologic complications. 9 In 20.4% of the cases, the oral metastasis was the first clinical sign of the malignancy; 3 frequently, malignant metastatic lesions of the oral soft tissues are confused with more benign entities, such as pyogenic granuloma, peripheral giant cell granuloma, peripheral fibroma, and periodontal abscess. 5,8,10 The lesion appeared as an ulceration in approximately only 10% of the cases.…”

Initial Presentation of Lung Sarcomatoid Carcinoma as a Metastatic Lesion in the Mandibular Gingiva

“…The most common primary site of tumor metastasis to the gingiva is the lung. The histologic types of metastatic lung cancers include squamous‐cell carcinoma, 5,6 adenocarcinoma, 7‐10 large‐cell carcinoma, 11 and undifferentiated carcinoma 12‐15 . Metastasis to the gingiva from sarcomatoid carcinoma of the lung is a novel finding, despite numerous variations in histologic interpretation and classification.…”

Gi̇ngi̇val Metastasi̇s From the Squamous Cell Carci̇noma of the Lung: A Case Report and Revi̇ew of the Li̇terature

“…31 In literature, SCC due to lung metastasis to the oral cavity is a very rare condition. Only Alandez et al 20 and…”