Metastatic Meningioma to the Liver Successfully Treated with a Wedge Resection and Radiation Therapy: Report of a Case

Abstract

Meningiomas account for approximately 15%-20% of all primary brain tumors. Metastatic meningiomas are rare. Less than 100 cases of extracranial metastatic meningiomas have been reported in the literature. An unusual case of metastatic meningioma to the liver successfully treated by a surgical resection and radiation therapy is presented.

Delayed Hepatic Metastasis From a Benign Fibroblastic Meningioma Thirty-One Years After Surgical Resection of the Intracranial Tumor

“…1 According to WHO criteria, the histologic grade of the tumor is the most important predictive factor for recurrence and metastasis. [2][3][4][5] However, metastatic meningioma may present in isolation without coexistent or previous local tumor recurrence, as seen in our patient. 3 However, these features are not essential for the occurrence of extracranial metastasis, and any histologically benign meningioma has the potential to metastasize.…”

“…1 Isolated hepatic or renal metastasis may also occur through the vertebral (meningorachidian) venous system, which connects the veins of the skull, spinal canal, and vertebral column to the thoracoabdominal wall. 4 The results after a subtotal resection and postoperative radiotherapy are similar to those seen after a complete surgical excision. Surgery seems to be the treatment of choice for resectable lesions.…”

“…4 The results after a subtotal resection and postoperative radiotherapy are similar to those seen after a complete surgical excision. 4 Postoperatively, recurrence in the residual liver can be treated with transarterial chemoembolization. Longterm local control and survival seem to be similar with all of the treatment modalities.…”

“…Surgery seems to be the treatment of choice for resectable lesions. 4 No definite therapeutic regimen has been established for metastatic meningiomas. 8 Radiation therapy, radiosurgery, and newer options that include stereotactic radiotherapy and intensity-modulated radiation therapy have been used with variable results that depend on the tumor location as well as staging.…”

Incidental Metastatic Meningioma Presenting as a Large Liver Mass

“…The major sites usually involved by meningioma include the lungs, axial bones, pleura, mediastinum, and lymph nodes [ 1 , 2 ]. Metastasis to the liver is rare [ 3 ] and are usually symptomatic [ 4 , 5 ] or may occur simultaneously with a meningioma occurring in the central nervous system (CNS) [ 6 , 7 ]. Metastatic meningioma to the liver can occur as a recurrence; years after a primary CNS meningioma has been surgically resected [ 8 , 9 ].…”