Metastatic Oat Cell Carcinoma of the Lung Producing Extrahepatic Bile Duct Obstruction

Howe, Harold R.; Hansen, Kimberley J.; Albertson, David A.

doi:10.1097/00007611-198511000-00042

Cited by 12 publications

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“…Surgical specimen from pulmonary resection revealing moderately differentiated squamous cell carcinoma with keratin pearl formation (hematoxylin and eosin stain, 3100).r 1997 WILEY-LISS, INC.Diagnostic Cytopathology, Vol 16,No 3 described in the literature, the patients suffered from symptoms of acute pancreatitis/obstruction,[3][4][5][6] accounting for the clinical symptoms in the present case.…”

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confidence: 74%

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Squamous cell carcinoma of the lung metastatic to the pancreas: Diagnosis by fine-needle aspiration biopsy

Mockli¹,

Silversmith

1997

Diagn. Cytopathol.

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confidence: 74%

“…[3][4][5][6] In many cases Typically, carcinoma metastatic to the pancreas presents as part of widespread disease, 1,3-6 although presentation as a single pancreatic mass does occur rarely, 2 as in this case.…”

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confidence: 99%

Squamous cell carcinoma of the lung metastatic to the pancreas: Diagnosis by fine-needle aspiration biopsy

Mockli¹,

Silversmith

1997

Diagn. Cytopathol.

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“…As a result, the initial presentation of jaundice at diagnosis of lung cancer is usually assumed to be the result of diffuse hepatic metastasis, a common finding in lung cancer. There are only several reported cases worldwide in the literature about lung cancer causing extrahepatic bile duct obstruction by pancreatic metastasis5-7).…”

Section: Discussionmentioning

confidence: 99%

Pancreatic Metastasis and Obstructive Jaundice in Small Cell Lung Carcinoma

Jeong

Kim²,

Lee³

et al. 2006

Korean J Intern Med

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Primary lung cancer frequently metastasizes to distant organs. The pancreas is a relatively infrequent site of metastasis. Furthermore, obstructive jaundice resulting from pancreatic metastasis is extremely rare. This paper examines the case of a 65-year-old woman with small cell lung cancer initially presenting with extrahepatic biliary obstruction. The patient underwent percutaneous transhepatic biliary drainage. The obstruction was relieved with a stent placement, then the woman was treated with combination chemotherapy (irinotecan, cisplatin) and a complete remission achieved in six months.

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“…The most common histological type of lung cancer that is related to pancreatic metastasis was reported as small cell lung cancer, followed by large cell carcinoma, squamous cell carcinoma, and adenocarcinoma 12,30,32–35. For metastasis-induced acute pancreatitis patients with lung cancer, the rate of small cell carcinoma to non-small cell carcinoma was 15/18 in one study and 5/15 in another study 8,36…”

Section: Frequency Of Pancreatic Metastasismentioning

confidence: 94%

Pancreatic involvement in small cell lung cancer

Gönlügür¹,

Mirici²,

Karaayvaz³

2014

Radiology and Oncology

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BackgroundFew data are available concerning incidence, clinical picture, and prognosis for pancreatic metastases of small cell lung carcinoma. In this paper we review the related literature available in English language.ConclusionsAlthough pancreatic metastases are generally asymptomatic, they can rarely produce clinical symptoms or functional abnormalities. The widespread use of multi-detector computerised tomography (CT) in contemporary medical practice has led to an increased detection of pancreatic metastases in oncology patients. Tissue diagnosis is imperative because radiological techniques alone are incapable of differentiating them from primary pancreatic tumours. Pancreatic metastases occur in the relative end stage of small cell lung cancer. The main complications of these lesions, although rare, are acute pancreatitis and obstructive jaundice. Early chemotherapy can provide a survival benefit even in patients with mild acute pancreatitis or extrahepatic biliary obstruction.

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Metastatic Oat Cell Carcinoma of the Lung Producing Extrahepatic Bile Duct Obstruction

Cited by 12 publications

References 0 publications

Squamous cell carcinoma of the lung metastatic to the pancreas: Diagnosis by fine-needle aspiration biopsy

Squamous cell carcinoma of the lung metastatic to the pancreas: Diagnosis by fine-needle aspiration biopsy

Pancreatic Metastasis and Obstructive Jaundice in Small Cell Lung Carcinoma

Pancreatic involvement in small cell lung cancer

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