Metastatic orbital tumors in southern China during an 18-year period

Yan, Jianhua; Gao, Shaohui

doi:10.1007/s00417-011-1660-6

Cited by 33 publications

(41 citation statements)

References 20 publications

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“…An Italian study, performed on 93 patients, found the greatest percentage of mammary origin (36%), followed by kidney (10%), lung (8%) and skin (6%) (14). Another study, carried out in Southern China on 46 patients, showed a higher percentage of nasopharyngeal origin (30%), followed by lung (8%), liver (6%), kidney (4%) and breast (4%) (15). Finally, a Japanese study, performed on 128 patients, found the greatest frequency of pulmonary origin (16%), followed by breast (15%), liver (14%), adrenal neuroblastoma (7%) and kidney (3%) (16).…”

Section: Discussionmentioning

confidence: 99%

Unilateral Blepharoptosis from Renal Cell Carcinoma

Greco

Sabatino

et al. 2016

jkcvhl

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Blepharoptosis is the drooping or inferior displacement of the upper eyelid. Blepharoptosis can be either congenital or acquired. Tumour metastasis is one of the acquired causes of blepharoptosis. The lungs, locoregional lymph nodes, bone and liver are the usual sites of metastases of renal cell carcinoma (RCC); however, unusual locations of RCC have also been reported. Herein, we describe a case of a 47-year-old man with unilateral ptosis and blurred vision due to metastatic RCC. We describe the different causes of blepharopstosis, the path that led to the diagnosis, and how RCC can metastasize to unusual anatomical regions such as the orbit. Symptoms such as exophthalmos, lid edema, diplopia, ptosis, cranial nerve paralysis or blurred vision may mime a benign disease; however, they could also be the symptoms of a systemic malignancy.

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Section: Discussionmentioning

confidence: 99%

Unilateral Blepharoptosis from Renal Cell Carcinoma

Greco

Sabatino

et al. 2016

jkcvhl

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“…As our case showed, a contrast-enhanced CT of the orbit or MRI establishes the diagnosis of orbital involvement. Metastasis appears as a high-density soft tissue mass of the involved orbit with a marked contrast enhancement 15. However, this imaging finding is non-specific.…”

Section: Discussionmentioning

confidence: 99%

“…Treatment for orbital metastasis is generally palliative. Systemic corticoids and chemotherapy can be used 7 15. But, orbital radiotherapy is the mainstay therapy and can improve orbital symptoms in 70–90% of cases and diminish the size of the tumour 16.…”

Section: Discussionmentioning

confidence: 99%

Orbital metastasis as the inaugural presentation of occult rectal cancer

et al. 2014

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Orbital metastasis is uncommon and occurs in 2-3% of patients with cancer. It is rarely the initial manifestation of a systemic malignancy. It usually indicates extensive haematogenous dissemination of a primary cancer and is associated with poor prognosis. Breast, lungs and prostate cancers are the most common primary cancers leading to orbital metastasis. However, orbital tumour revealing a rectal adenocarcinoma is exceptional. We describe a case of orbital tumour in a 67-year-old man with no history of systemic cancer while presenting with ophthalmic symptoms. Investigations revealed rectal adenocarcinoma as the primary malignant tumour.

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“…In southern China, the most common primary cancer that metastasizes to the orbit is nasopharyngeal carcinoma (30.34%), followed by lung cancer and liver cancer [5]. There is no exact information about the most common type of NPC in Syria.…”

Section: Discussionmentioning

confidence: 99%

A Rapidly Progressive Proptosis, a Case Report

Tajdini¹,

Sinjab²,

Hassan³

2012

OJOph

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In contrast to intraocular metastases, orbital metastases are a rare manifestation of systemic malignancies; such orbital metastases account for only 1% -13% of all orbital tumors [1]. Such tumors grow rapidly; they may undergo necrosis, as the rate of tumor angiogenesis cannot keep pace with the rapidly expanding mass. Here, we report a rare case of an orbital metastasis from a nasopharyngeal carcinoma.

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Metastatic orbital tumors in southern China during an 18-year period

Cited by 33 publications

References 20 publications

Unilateral Blepharoptosis from Renal Cell Carcinoma

Unilateral Blepharoptosis from Renal Cell Carcinoma

Orbital metastasis as the inaugural presentation of occult rectal cancer

A Rapidly Progressive Proptosis, a Case Report

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