Metastatic Papillary Thyroid Cancer Diagnosed and Treated during Pregnancy

İsmi, Onur; Cinpolat, Ovgu; Gen, Ramazan; Vayısoğlu, Yusuf; Görür, Kemal; Özcan, Cengiz

doi:10.5152/tao.2016.1454

Cited by 2 publications

(5 citation statements)

References 12 publications

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“…Many studies have reported the option to operate during pregnancy due to the anxiety caused by cases of more aggressive tumors 2,8,12,13,19 , as it occurred in the cases herein reported. Aggressive, or locally advanced histology, cervical metastases, compressive symptoms, and rapid nodule growth [13][14][15]18,20 are the main aggressiveness criteria adopted to indicate surgery in the second trimester, as it occurred in the case of the present study, showing excellent results.…”

Section: /9mentioning

confidence: 83%

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Thyroid cancer surgical indication during pregnancy: systematic literature review and series of illustrative cases

Chinelatto¹,

Hojaij²,

Carlucci³

et al. 2020

Arch. Head Neck Surg.

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Introduction: Thyroid papillary carcinoma is the second most frequent type of cancer during pregnancy. Its diagnosis is related to patient fear and anxiety. There is little consensus on when to perform surgery in those cases. Objective: To evaluate and discuss timing possibilities for surgical treatment in thyroid cancer in pregnant women. Methods: Systematic literature review based on online search at the Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) and National Center for Biotechnology Information (NCBI) databases. Retrospective analysis of thyroidectomies performed in the second trimester of pregnancy by the authors between 1999 and 2019. Results: The systematic review included nine articles. Their conclusions diverge with respect to the optimal timing of thyroid surgery. The medical literature considers thyroidectomy after safe delivery. The most recent studies are more flexible regarding carrying out this surgery during the second trimester of pregnancy. In the authors' experience (n=5), surgical treatment during the second trimester of pregnancy is a good option for more aggressive tumors. Conclusion: More aggressive cases of thyroid papillary carcinoma can be treated with surgery during the second trimester of pregnancy. Performing the surgery after delivery is safer in the case of less aggressive cancer cases. The decision should consider hospital costs, surgery risks, and patient anxiety in relation to cancer.

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Section: /9mentioning

confidence: 83%

“…Only cases considered serious according to author discretion Yasmeen et al 3 Rosen et al 9 Moosa and Mazzaferri 8 Boucek et al 4 Gietka-Czernel et al 11 Nam et al 6 Ismi et al 12 Kuy et al 10 Uruno et al 1…”

Section: After Delivery Any Casementioning

confidence: 99%

Thyroid cancer surgical indication during pregnancy: systematic literature review and series of illustrative cases

Chinelatto¹,

Hojaij²,

Carlucci³

et al. 2020

Arch. Head Neck Surg.

View full text Add to dashboard Cite

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“…Eleven case reports were included in our study, from which five case reports referred to cervical or distant metastasis diagnosed during pregnancy ( 32 - 36 ). Three case reports outlined the surgical treatment during pregnancy, while one reported surgery in postpartum ( 36 - 39 ). Two case reports suggested multidisciplinary team for the management of metastatic well-DTC during pregnancy ( 40 , 41 ).…”

Section: Resultsmentioning

confidence: 99%

“…Some studies suggest that surgery is eligible during the second trimester of pregnancy, while others suggest surgery after delivery with active surveillance. Case reports have been published reporting surgery in different stages of gestation ( 36 - 39 ). A retrospective study in 2014 concludes that surgery in second trimester is acceptable but in non-aggressive cases of DTC, surgery after delivery is recommended ( 25 ).…”

Section: Discussionmentioning

confidence: 99%

“…Based on this fact, Modesti et al suggested that cervical plexus block and conscious sedation is a safe alternative for surgeries that cannot be delayed ( 26 ). Indications for surgery in DTC during pregnancy are based on the histological type, the growth speed, extrathyroidal spread, compression symptoms, suspicious lymph node or metastasis ( 36 , 43 ).…”

Section: Discussionmentioning

confidence: 99%

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Thyroid cancer and pregnancy: a systematic ten-year-review

Panagiotakopoulos,

Chorti,

Pliakos

et al. 2024

Gland Surg

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Background Thyroid cancer is the second most common malignancy during pregnancy, especially the well-differentiated thyroid cancer (well-DTC). Therefore, complex medical and social dilemmas arise, dealing with which requires deep knowledge of the nature and characteristics of the disease and pregnancy as a whole. The purpose of this review is to present the diagnostic and therapeutic strategies of thyroid cancer during pregnancy and the postpartum period. Methods Extended review of the literature [2011–2023] was performed. Two hundred ninety-six articles were found, from which 225 were excluded due to irrelevant subjects. Seventy-one articles were assessed for eligibility, from which 33 articles were cohort studies and case reports and were included in the review. Results From the 33 included studies, 18 were retrospective cohort studies, 1 was cohort study, 2 were case control studies, 1 was meta-analysis and 11 were case reports. The primary endpoints of these studies refer to the progression and recurrence of DTC during pregnancy, the prevalence of thyroid cancer in pregnancy and the most appropriate time for surgical intervention. Conclusions The majority of the studies agree that well-differentiated tumors with mild clinical and imaging characteristics do not require immediate surgical treatment, but mere monitoring. Surgery can be delayed after childbirth. In contrast, tumors with aggressive behavior as well as non-differentiated ones, require immediate surgery because delay under these circumstances can dramatically reduce survival rates. Finally, a history of thyroid cancer does not seem to affect future deliveries, on condition that no residual disease exists at the onset of pregnancy.

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Metastatic Papillary Thyroid Cancer Diagnosed and Treated during Pregnancy

Cited by 2 publications

References 12 publications

Thyroid cancer surgical indication during pregnancy: systematic literature review and series of illustrative cases

Thyroid cancer surgical indication during pregnancy: systematic literature review and series of illustrative cases

Thyroid cancer and pregnancy: a systematic ten-year-review

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