Metastatic paraganglioma

Abstract

A man in his 70s, with a history of a glomus jugulare paraganglioma diagnosed 18 years ago, presented with an unprovoked deep vein thrombosis (DVT). The paraganglioma had been treated by radiotherapy, and yearly scans had not shown any progression since treatment. A sclerotic focus in L4 vertebral body was reported on a CT scan of the neck and trunk which was done to exclude a neoplastic process being the precipitating factor for the DVT. Nuclear imaging showed multiple areas of bony uptake, suggestive of metastases. A bone biopsy of the left femur resulted positive for metastatic paraganglioma. A monthly intramuscular injection of octreotide 30 mg was prescribed.

An Unexpected Diagnosis of Femoral Paraganglioma: A Case Report

“…Its incidence rate is exceptionally low, and the occurrence of paraganglioma within bone is even rarer. In the course of our literature review, we came across only two case reports of femoral metastasis subsequent to Pheochromocytoma resection [4,5].…”