Metastatic paranasal sinuses adenocarcinoma from breast carcinoma, a rare event: a case report

Khurayzi, Tawfiq; Al-Shahrani, Abdullah M

doi:10.18203/issn.2454-5929.ijohns20174340

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…2 However, ethmoidal deposits are the primary site of just 14% of paranasal metastases 1 and can progress asymptomatically until ocular symptoms occur, such as with the orbital apex syndrome seen in our patient (defined as opthalmoplegia, chemosis and proptosis of the affected eye). 3 The disease may initially act, as in this case, as a radiological mimic for far more common pathologies such as acute or chronic ethmoiditis.…”

Section: Discussionmentioning

confidence: 98%

Ethmoidal metastasis as a first presentation of breast cancer: a case report

Maity

Vasani

Alusi

2018

annals

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Distant metastasis in advanced breast cancer is not uncommon; however, spread to the paranasal sinuses is extremely rare. We present a case of a woman who presented to our ophthalmology colleagues with worsening unilateral proptosis secondary to a tumour mass within her ethmoid sinuses. Biopsy of the ethmoid tumour showed adenocarcinoma of unknown origin. Whole-body positron emission computed tomography demonstrated a breast primary lesion. The patient was treated with palliative chemotherapy, and the patient remains well at this point. The importance of specialist head and neck radiological interpretation of imaging cannot be underestimated. Early tissue diagnosis is essential before ascribing patients with orbital symptoms to non-malignant process.

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Section: Discussionmentioning

confidence: 98%

Ethmoidal metastasis as a first presentation of breast cancer: a case report

Maity

Vasani

Alusi

2018

annals

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Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis

Othman¹,

Zahedi

Husain

2020

Case Reports in Medicine

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Breast cancer metastases to the base of the skull with concomitant infiltration into the paranasal sinuses and nasopharynx are exceptionally rare with only small numbers of reported literatures. Greenberg et al. in 1981 described five clinical syndromes with regards to the base of skull metastases and the clinical presentation of each syndrome related to its anatomical location. Often, metastases to the base of the skull remain asymptomatic until the lesion has increased to a considerable size causing bony destruction and impingement to the surrounding structures. When involving the paranasal sinuses or nasopharynx, the most common presenting symptoms mimic those of rhinosinusitis and, hence, may delay the accurate diagnosis. We are reporting a case of base of skull metastasis from breast carcinoma, 23 years after the primary diagnosis. To the best of our knowledge, our case is the first case to report latent metastasis of more than 20 years.

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Metastatic paranasal sinuses adenocarcinoma from breast carcinoma, a rare event: a case report

Cited by 2 publications

References 17 publications

Ethmoidal metastasis as a first presentation of breast cancer: a case report

Ethmoidal metastasis as a first presentation of breast cancer: a case report

Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis

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