Metastatic solid tumors to the testis: a clinicopathologic evaluation of 157 cases from an international collaboration

Nova-Camacho, Luiz M.; Acosta, Andrés M; Trpkov, Kiril; Sangoi, Ankur R.; Aimar, Pierre; Chou, Angela; Yilmaz, Aslı; Morini, Aurélien; Rodrigues, Ângelo; Fletcher, Christopher D.�M.; Montiel, Delia Pérez; Maclean, Fiona; Contreras, F.; Queipo, Francisco; Unamunzaga, Gorka Muñiz; Mesa, Hector; Torres, Inés de; Ruiz, Irune; Alvarado‐Cabrero, Isabel; Lobo, João; Schwartz, Lauren E.; Liu, Cheng; Akgul, Mahmut; García-Martos, María; Palmer, Matthew; Aron, Manju; Raspollini, Maria Rosaria; Celada, Manuel Manrique; Hwang, Michael; Idrees, Muhammad T.; Rioux‐Leclercq, Nathalie; Zalles, Nicole; Vergara, Norge; Lal, Priti; Wobker, Sara E.; Kammerer‐Jacquet, Solène‐Florence; Prendeville, Susan; Tilmant, Théau; Ulbright, Thomas M.; Verkarre, Virginie; Collins, Katrina; Williamson, Sean R.; Panizo, Ángel

doi:10.1016/j.humpath.2023.06.002

Human Pathology

2023

DOI: 10.1016/j.humpath.2023.06.002

|View full text |Cite

Metastatic solid tumors to the testis: a clinicopathologic evaluation of 157 cases from an international collaboration

Luiz M. Nova-Camacho

Andrés M Acosta

Kiril Trpkov

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Ultrasonographic characteristics of testicular renal cell carcinoma metastasis: A case report and literature review

Gökçek,

Koptay,

Özkan

2024

J of Clinical Ultrasound

View full text Add to dashboard Cite

Renal cell carcinoma (RCC) extremely rarely metastasizes to the testis. To date, only three reports have documented bilateral testicular metastasis of RCC. Here, we review the ultrasonographic characteristics of testicular metastasis of renal cell carcinoma cases in the literature and present a 43‐year‐old patient with von Hippel–Lindau (VHL) disease who was diagnosed with bilateral testicular metastasis of RCC many years after nephrectomy, with ultrasonographic‐pathological correlation.

show abstract

Ultrasonographic characteristics of testicular renal cell carcinoma metastasis: A case report and literature review

Gökçek,

Koptay,

Özkan

2024

J of Clinical Ultrasound

View full text Add to dashboard Cite

show abstract

Metastatic Lung Adenocarcinoma Presenting as Hydrocele

Gupta,

Erickson

2023

Mayo Clinic Proceedings

View full text Add to dashboard Cite

Origin and outcome of metastatic tumours to the testes: a nationwide study

Woortman,

van Leenders,

Hugen

et al. 2023

BJU International

View full text Add to dashboard Cite

ObjectivesTo perform a retrospective cohort analysis for metastatic tumors in the testes to explore the timing, presentation and prognosis of this particular type of metastases and the factors that influence outcome.Patients and methodsA nationwide retrospective review of pathology reports of patients with pathologically confirmed metastases to the testis between 1991 and 2021 was performed. Data was collected from the Dutch nationwide pathology databank (PALGA) and the Dutch Cancer Registry (NCR). Log‐rank testing and Kaplan‐Meier analyses were used to assess overall survival, and Cox proportional hazard models were used for multivariate survival analysis.ResultsA total of 175 patients with a testicular metastasis were included. The median age at diagnosis of testicular metastasis was 67 years (range 3‐88). Testicular metastases originated from a variety of primary tumors, though most frequently from the prostate (40.6%), kidney (13.7%), colon (10.3%), bladder (7.4%), and skin (5.7%). Synchronous testicular metastasis was detected in 53 cases, while 114 metachronous lesions were found after a median interval of 22 months (IQR 1‐53) after the original cancer diagnosis. Overall survival after the diagnosis of a testicular metastasis was poor with a median survival of 14.2 months (95% CI 10.2 – 18.3). The primary tumor origin was an independent factor for survival, with worst survival for patients with primary skin, bladder and colon cancer.ConclusionTesticular metastases are very uncommon and arise mainly from primary tumors anatomically close to the testes. Most patients develop metachronous testicular metastasis in an oligometastatic disease stage. These metastases have invariably poor survival.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Metastatic solid tumors to the testis: a clinicopathologic evaluation of 157 cases from an international collaboration

Cited by 3 publications

References 30 publications

Ultrasonographic characteristics of testicular renal cell carcinoma metastasis: A case report and literature review

Ultrasonographic characteristics of testicular renal cell carcinoma metastasis: A case report and literature review

Metastatic Lung Adenocarcinoma Presenting as Hydrocele

Origin and outcome of metastatic tumours to the testes: a nationwide study

Contact Info

Product

Resources

About