Metastatic Thymic Adenocarcinoma from Colorectal Cancer

Abstract

This report describes the case of a 57-year-old man with an anterior mediastinal tumor. Four years previously, he underwent laparoscopic anterior resection for sigmoid colon cancer. Thirty months after that procedure, bilateral pulmonary metastasectomy was performed. Twelve months later, follow-up computed tomography revealed a 1-cm pulmonary nodule on the upper lobe of the right lung and a solid mass on the anterior mediastinum, and the patient was also observed to have an elevated serum carcinoembryonic antigen (CEA) level. Repeated pulmonary nodule resection and total thymectomy were performed. Immunohistochemical staining of the anterior mediastinal tumor revealed adenocarcinoma, and his serum CEA level returned to normal after the operation. These findings strongly suggested metastatic thymic adenocarcinoma from a colorectal cancer.

Colorectal Cancer Metastasis to the Thymus Gland: Rare Presentation of Colorectal Cancer as Anterior Mediastinal Mass

“…To our knowledge, only one case of colorectal adenocarcinoma metastasizing to the thymus gland has been documented, by Lee et al in 2015 [5]. This case report details our experience with a rare case of colorectal metastasis to the thymus gland in a young, healthy male.…”

A case of thymic basaloid carcinoma with rectal carcinoma

“…It is said that other malignant tumors occur in about 30% of patients with thymoma, and colorectal cancer is the highest incidence [ 2 ]. On the other hand, there is only one report of thymic metastasis of colorectal cancer [ 6 ], and no report of colorectal metastasis of thymic cancer. Therefore, co-occurrence of thymoma and rectal cancer is most likely and if possible, both should be radically operated.…”

Thymic and Mediastinal Lymph Node Metastasis of Colon Cancer

“…As the next step, the tumor cells have been suggested to seed in various organs, such as the bone, brain, and any other sites via the pulmonary vein [1,2]. Metastatic thymic adenocarcinoma from extra thymic malignancies is rare [3,4]. Moreover, thymic metastasis from colorectal cancer is extremely rare [4].…”