Metastatic transitional cell carcinoma of the bladder arising in a patient with bladder autoaugmentation

Mehan, Rahul; Misseri, Rosalia; VanderBrink, Brian A.; Rink, Richard C.; Beck, Stephen D.W.

doi:10.1016/j.jpurol.2010.07.007

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…Proposed risk factors of developing bladder malignancy in SB patients are chronic urinary tract infection, stone disease and catheterisation and surgery incorporating enteric segments into the lower urinary tract like enterocystoplasty [2]. The latter procedure is often performed in patients with a low functional bladder capacity.…”

Section: Discussionmentioning

confidence: 99%

“…One of the possible advantages could be the lower risk of developing bladder carcinoma. Detrusorectomy is not a known risk factor and has only been reported once before (in a 20-year-old patient who had pT2N2Mx disease and eventually died 15 months after onset of symptoms) [2]. It is important to realise that bladder carcinoma not only develops in patients who underwent augmentation using enteric segments.…”

Section: Discussionmentioning

confidence: 99%

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Bladder carcinoma in a 31-year-old female spina bifida patient with an auto-augmented bladder

Veenboer

Kort

2011

Int Urol Nephrol

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We present the case of a 31-year-old spina bifida patient presenting with a poorly differentiated T3N1M0 bladder carcinoma with sarcomatoid differentiation in an auto-augmented bladder. She underwent a radical cystectomy and a bilateral lymph node dissection. However, only 10 months after the onset of her symptoms, she died after major lymphatic metastases had developed in the small pelvis. This case report is the first on an adult spina bifida patient developing bladder carcinoma after detrusorectomy. It shows that bladder cancer also occurs in patients who underwent detrusorectomy, despite the fact that the risk is supposedly lower than in patients who underwent enterocystoplasty. Moreover, tumour spread to adjacent organs could occur more rapidly in auto-augmented bladders because of the lack of muscle tissue. The latter could have serious implications on the prognosis of these patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Bladder carcinoma in a 31-year-old female spina bifida patient with an auto-augmented bladder

Veenboer

Kort

2011

Int Urol Nephrol

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“…The management for neurogenic bladder involves intermittent or permanent catheterization, use of anticholinergic drugs, and surgical intervention, such as augmentation cystoplasty. 2 …”

Section: Introductionmentioning

confidence: 99%

A Large Bladder Tumor Covered With a Thick “Shell” of Necrotic Material

Wang¹,

Zhou

Gong

et al. 2016

Medicine

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Bladder tumor arising in a spina bifida patient is rare and may be clinically latent.We report the case of a 61-year-old female patient with spina bifida, neurogenic bladder, and a history of recurrent urinary tract infections. A B-ultrasound and non-contrast computed tomography scan did not reveal any bladder mass, but an unexplained “well-filled” bladder was observed, which was confusing as the catheter was present and open. However, a subsequent cystoscopic evaluation revealed a large bladder mass measuring 9.5 × 9.0 × 6.5 cm3, which almost filled the entire bladder. The mass had coarse and flocculent surface and seemed to be free from each observed wall of the urinary bladder. It was diagnosed as an infectious necrotic mass based on its appearance.During transurethral resection of the mass, a bladder tumor was suspected as small blood vessels and bleeding appeared within the inner layer of the mass. Pathological examination revealed necrotic material, inflammatory cells, and urothelial carcinoma cells. Then, a radical cystectomy was performed, and the pathological results indicated stage pT3bN0M0 transitional cell carcinoma. In the gross specimen, the base of the tumor measured 3 × 3 cm2 on the top of the back wall of the bladder.Bladder tumors may have atypical presentations in patients with spina bifida. Regular screening is helpful for earlier detection and improving outcomes of bladder tumors in such patients.

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Urinary considerations for adult patients with spinal dysraphism

et al. 2015

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The incidence of newborns with spinal dysraphism is diminishing worldwide, although survival of individuals with this condition into adulthood continues to improve. The number of adults with spinal dysraphism will, therefore, increase in the coming years, which will pose new challenges in patient management. Urological manifestations of spinal dysraphism can include increased risks of urinary incontinence, urinary tract infection, urinary calculi, sexual dysfunction, end-stage renal disease and iatrogenic metabolic disturbances; however, the severity and incidence of these symptoms varies substantially between patients. Owing to the presence of multiple comorbidities, treatment and follow-up protocols often have to be adapted to best suit the needs of specific patients. Authors describe bladder and kidney function and long-term complications of treatments initiated in childhood, as well as the potential for improvements in quality of life through better follow-up schedules and future developments.

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Metastatic transitional cell carcinoma of the bladder arising in a patient with bladder autoaugmentation

Cited by 3 publications

References 19 publications

Bladder carcinoma in a 31-year-old female spina bifida patient with an auto-augmented bladder

Bladder carcinoma in a 31-year-old female spina bifida patient with an auto-augmented bladder

A Large Bladder Tumor Covered With a Thick “Shell” of Necrotic Material

Urinary considerations for adult patients with spinal dysraphism

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