Metastatic Tumors of the Penis: A Review of the Literature and a Report of Two Cases

Abeshouse, Benjamin S.; Abeshouse, George A.

doi:10.1016/s0022-5347(17)65117-6

Cited by 189 publications

(119 citation statements)

References 33 publications

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“…Priapism was the clinical presentation of 27% of secondary penile tumours in a series by Chaux and colleagues 2 and their review found that up to 40% of patients may present similarly. 8 Although a visible penile tumour was absent in our case, most patients (80%) in the aforementioned series presented with it, 2 which is consistent with previous reviews. 6,7 Pain, skin changes, hematuria and obstructive voiding symptoms were rarer presentations.…”

Section: Discussionsupporting

confidence: 91%

Urothelial carcinoma involving the distal penis

Dason

Sheikh

Wang

et al. 2012

CUAJ

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Urothelial carcinoma (UC) rarely metastasizes to the penis and skin. We report the case of a 73-year-old man with UC metastases to the corpus spongiosum and dermis of the distal penis. We also review the clinicopathologic characteristics and management options for UC metastasizing to the penis. The patient presented with priapism and edema of the genital region. This follows a 5-year history of urothelial carcinoma in situ that progressed to invasive cancer despite intravesical immunotherapy. Seventeen months prior to presentation, the patient underwent a radical cystectomy with adjuvant chemotherapy. The cystectomy specimen demonstrated a pT4a N2 M0 G3 UC and margins were positive for carcinoma in situ. Follow-up had been negative for recurrence until his presentation with priapism. Incisional biopsy of the glans revealed UC and radical penectomy was performed with negative margins. The penile specimen demonstrated extensive involvement of the corpus spongiosum by UC with lymphovascular invasion and subepidermal involvement. Three months after penectomy, the patient presented with inguinal nodal recurrence. Palliative radiotherapy was administered and the patient passed away eight months after surgery.

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Section: Discussionsupporting

confidence: 91%

Urothelial carcinoma involving the distal penis

Dason

Sheikh

Wang

et al. 2012

CUAJ

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“…[4] It is reported that occlusion of the draining veins or secondary to thrombosis in the cavernosal spaces grounded on the infiltrating tumour cells could cause priapism. [10] It is a common feature in most of the patients with hematologic secondary malignancy. [11] It was observed that pain is not one of the prominent symptoms in most patients, and when present, it is partly in the penis and partly in the perineum.…”

Section: Discussionmentioning

confidence: 99%

Penile metastasis of rectal cancer: case report

Nalbant

Tuygun

Imamoğlu

et al. 2015

CRCP

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Genitourinary and colon tumors which constitutes frequent sources to metastatic tumors of the penis, are relatively more common tumors in the society. Though its rich vascularization, metastatic tumor of the penis is very rare. This can be considered to be a gladsome situation in terms of hopeless survey of metastatic penile tumors. The main goal of treatment is to improve the comfort and quality of life in selected patients while it may not contribute to surveillance.

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“…[8] Since then few reports of metastatic penile carcinoma from primary tumor in rectum have been described in literature. [3][4][5][6][7] The most commonly accepted modes of spread to penis are through (1) retrograde venous spread (2) retrograde lymphatic spread (3) arterial spread (4) direct extension and (5) secondary embolization.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5][6][7] Patients with penile metastasis usually have widespread metastatic disease. [8] We report here a case of adenocarcinoma of rectum with isolated penile metastasis.…”

Section: Introductionmentioning

confidence: 93%