Metastic tumors of the orbit: A retrospective study

Holland, Detlef; Maune, Steffen; Kovács, G; Behrendt, S.

doi:10.1076/orbi.22.1.15.14007

Cited by 48 publications

(29 citation statements)

References 29 publications

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“…With orbital metastases from TCC, there is a poorer prognosis than with common metastatic tumors to the orbit, such as from the breast. 1 The patient in the present case was treated with a combination of radiation therapy and systemic chemotherapy with methotrexate, epirubicin, and cisplatin, and was the second longest surviving patient among all reported cases.…”

Section: Discussionmentioning

confidence: 89%

Metastasis to the Orbit from Transitional Cell Carcinoma of the Bladder

et al. 2006

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Section: Discussionmentioning

confidence: 89%

Metastasis to the Orbit from Transitional Cell Carcinoma of the Bladder

et al. 2006

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“…In yet another series of 21 cases with orbital metastasis, we observe that the latter originated in the mammary gland in 67% of cases and in skin melanoma in 14% of cases (15). In another study of 20 cases, the origin was the mammary gland in 40% of cases, prostate in 10% and lung in 10% (16). A bibliographical review published in 1990 shows results obtained for the origin of metastases: 42% originated in the mammary gland, 11% in lungs, 8,3% in the prostate, 5.2% are melanomas and 3.2% in kidneys.…”

Section: Discussionmentioning

confidence: 91%

“…Asides from these spots, orbital metastasis has also been found in the bladder (16,21), intestinal tract and throat (16,22,23), malignant solitary fibrous tumor in thorax (24), neuroendocrine tumor (25), dermatofibrosarcoma (26), renal medullar carcinoma (27), pleural mesothelioma (28), perineal alveolar rhabdomyosarcoma (29), pelvic teleangietatic osteosarcoma (30), spermatic cord leiomyosarcoma (31), ganglioneuroblastoma of the adrenal (32), forearm synovial sarcoma (33), pancreatic islets (34), hepatocellular liver carcinoma (35) and cervix (36) among others. In our 4-case series, location of the primary tumor matches the most frequently reported originating spots.…”

Section: Discussionmentioning

confidence: 99%

Metástasis orbitarias: Serie de cuatro casos y revisión de la literatura

González

López

2006

Arch Soc Esp Oftalmol

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Objective: To report four cases of orbital metastases and review the literature related to this condition. Methods:We reviewed the clinical records of the four patients and the appropriate world literature. Results: Two women 51 and 82 years old presented with orbital metastases from a primary breast tumour and a third woman (45 years old) had orbital metastases from a primary lung tumour. One man 60 years old presented with a metastases from a renal tumour. Two patients, one with breast metastases and the one with lung metastases, died of their disease. The remaining two patients are still alive with stable disease at the time of writing this report. Conclusion:The metastases in our series originated from tumours that frequently produce orbital metastases-the breast, lung and kidney. The clinical characteristics of the orbital syndromes they caused were similar to those reported in the literature. The clinical presentation was torpid in three cases and had a fulminating course in the ORIGINAL ARTICLE RESUMEN Objetivo: Describir cuatro casos clínicos de metás-tasis orbitarias y hacer una revisión de la literatura sobre esta patología. Métodos: Revisión de historias clínicas y de la bibliografía. Resultados: Dos mujeres de 51 y 82 años de edad presentaron una metástasis orbitaria procedente de un tumor de mama y una tercera (45 años de edad) de una neoplasia pulmonar. Un paciente varón de 60 años de edad presentó una metástasis orbitaria procedente de un tumor renal. Dos de los pacientes, una paciente con metástasis de tumor de mama y la paciente con metás-tasis de tumor pulmonar, fallecieron a consecuencia de su tumor primario, la primera a los dos años y medio y la segunda dos meses después de los primeros signos de metástasis orbitaria. Los otros dos pacientes continúan vivos en situación estable. Conclusiones: Las metástasis en nuestra serie se originaron en tumores de mama, pulmón y riñón, que se encuentran entre los tumores que con más frecuencia producen metástasis orbitarias. Las características clínicas del síndrome orbitario coin-452 ARCH SOC ESP OFTALMOL 2006; 81: 451-462 GONZÁLEZ F, et al.

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“…The most common neoplastic lesions in the cavernous sinus result from direct invasion by parasellar lesions (eg, pituitary adenoma, craniopharyngioma, meningioma, chordoma), perineural spread fr om hea d and neck m alig nancies, or hematogenous spread from distant cancers (eg, breast, prostate, lung, lymphoma) [3,22]. Tumors that commonly invade the orbit include meningiomas, metastatic tumors (eg, breast, prostate, melanoma), cavernous hemangiomas, and plasma cell tumors [23,24]. A history of systemic malignancy, especially involving the head or neck, should be sought and the physical examination should be meticulous for signs of malignancy.…”

Section: Neoplasticmentioning

confidence: 99%

Painful ophthalmoplegia: Overview with a focus on tolosa-hunt syndrome

Gladstone

Dodick

2004

Current Science Inc

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Painful ophthalmoplegia is an important presenting complaint to emergency departments, ophthalmologists, and neurologists. The etiological differential diagnosis of painful ophthalmoplegia is extensive and consists of numerous sinister etiologies including vascular (eg, aneurysm, carotid dissection, carotid-cavernous fistula), neoplasms (eg, primary intracranial tumors, local or distant metastases), inflammatory conditions (eg, orbital pseudotumor, sarcoidosis, Tolosa-Hunt syndrome), infectious etiologies (eg, fungal, mycobacterial), and other conditions (eg, microvascular infarcts secondary to diabetes, ophthalmoplegic migraine, giant cell arteritis). A systematic approach to the evaluation of painful ophthalmoplegia can lead to prompt recognition of serious disorders that if left untreated, can be associated with significant morbidity or mortality. Inflammatory conditions such as Tolosa-Hunt syndrome and orbital pseudotumor are highly responsive to corticosteroids, but should be diagnoses of exclusion.

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Metastic tumors of the orbit: A retrospective study

Cited by 48 publications

References 29 publications

Metastasis to the Orbit from Transitional Cell Carcinoma of the Bladder

Metastasis to the Orbit from Transitional Cell Carcinoma of the Bladder

Metástasis orbitarias: Serie de cuatro casos y revisión de la literatura

Painful ophthalmoplegia: Overview with a focus on tolosa-hunt syndrome

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