Knowledge of the day-to-day dynamics of surface urban heat island (SUHI) as well as their underlying determinants is crucial to a better design of effective heat mitigation. However, there remains a lack of a globally comprehensive investigation of the responsiveness of SUHI variations to meteorological variables. Based on the MODIS LSTs and auxiliary data in 2017, here we investigated 10,000+ cities worldwide to reveal day-to-day SUHI intensity (SUHII) variations (termed as SUHIIdv) in response to meteorological variables using Google Earth Engine. We found that: (1) meteorological variables related to the thermal admittance, e.g., precipitation, specific humidity and soil moisture (represented by daily temperature range in rural area, DTRr), reveal a larger regulation on SUHIIdv than those related to the air conditions (e.g., wind speed and near-surface air temperature) over a global scale. (2) Meteorological regulations on SUHIIdv can differ greatly by background climates. The control of specific humidity on SUHIIdv is significantly strengthened in arid zones, while that of wind speed is weakened prominently in equatorial zones. SUHIIdv is more sensitive to soil moisture in cities with higher background temperatures. (3) All meteorological variables, except that related to soil moisture (DTRr), show larger impact on SUHIIdv with antecedent precipitation over the global scale. Precipitation is observed to mitigate the SUHIIdv globally, and such effects are even more pronounced in equatorial and arid zones. We consider that our findings should be helpful in enriching the knowledge of SUHI dynamics on multiple timescales.