Meteorological Parameters and the Onset of Chest Pain in Subjects with Acute ST-Elevation Myocardial Infarction: an Eight-Year, Single-Center Study in China

Abstract

Objective: The purpose of this study was to investigate the influence of weather on the occurrence of acute ST-elevation myocardial infarction in Chinese subjects. Methods: Weather and climate data, as well as the occurrence of STEMI, were monitored at 2 am, 8 am, 2 pm, and 8 pm between 2003 and 2010. Generalized additive Poisson models were utilized to plot the numbers of patients with STEMI within 6 hour intervals against climatological variations, after accounting for the effects of the hour and season. Results: The inclusion of meteorological conditions, including observed atmospheric pressure (hPa, hectopascal) variations during the previous three hours and temperature (°C, degrees Celsius), significantly affected the occurrence of STEMI, as measured every six hours. Compared with the 50th percentile of atmospheric pressure variations, the RRs (95% CI) for the first percentile, 10th percentile, 25th percentile, 75th percentile, 90th percentile, and 99th percentile of atmospheric pressure variation over lag 0 were 1.66 (1.36∼2.03), 1.47 (1.30∼1.67), 1.22 (1.12∼1.33), 1.16 (1.07∼1.25), 1.27 (1.13∼1.43), and 1.16 (0.92∼1.46), respectively. Compared to the 50th percentile of temperature, the RRs (95% CI) for the first percentile, 10th percentile, 25th percentile, 75th percentile, 90th percentile, and 99th percentile of temperature over lag 0 were 0.58 (0.40∼0.83), 0.60 (0.46∼0.78), 0.69 (0.57∼0.83), 1.33 (1.14∼1.56), 1.39 (1.13∼1.71), and 1.17 (0.84∼1.63), respectively. Conclusions: Based on the eight-year, single-center study, significant relationships were observed among the occurrence of STEMI and atmospheric pressure variations during the previous three hours and temperature after account for long-term time trends.

Impact of Temperature Variation on Acute Myocardial Infarction in Karachi, Pakistan

“…Some of the studies have reported the association and role of atmospheric pressure in AMI; on the contrary, in our study atmospheric pressure failed to show significance [10,14]. Relative humidity and temperature variation and the difference between the maximum and minimum temperature for the day were found to be positively related to the number of primary PCI procedures; however, relative humidity (%) was insignificant in the subgroup analysis of the cold and warm seasons.…”

“…A direct comparison of our study finding with previous studies is difficult owing to the differences and inconsistencies in the study design and statistical methods. On an aggregate level, we observed the same relationship between temperature and AMI, along with with the same seasonal variations, as the studies conducted in the past [5,[9][10][11][12][13][14][18][19][20]. Among other metrological variables, temperature variations have a profound and consistent impact on the incidence of AMI, not only in its extreme states (both high and low) but also transient change in temperature can trigger acute myocardial infarction (AMI) [5].…”

“…Traditionally AMI is considered a disease of hot and humid weather. Moreover, in the past few decades, environmental triggers of AMI have gained mounting evidence from various geographies of the world [5,[7][8][9][10][11][12][13][14]. Low temperature or cold weather was found to be a convincing risk factor for the incidence of AMI [5,7].…”

Grey relation between main meteorological factors and mortality

“…These diseases may then cause increase in mortality. Even in some other studies in which air pressure was regarded as a confounding factor, the effect of air pressure is still not negligible (Rakers et al, 2016;Jia et al, 2014;Schwartz et al, 2015).…”