Methemoglobinemia after transesophageal echocardiography: a life-threatening complication

Jacka, Michael J.; Kruger, Marelise; Glick, Naomi

doi:10.1016/j.jclinane.2005.04.008

Cited by 14 publications

(8 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The presence of oxidising agents in blood can induce significant methaemoglobinaemia 6. Some of the common oxidising agents are nitrites, aniline dyes, antimalarial agents and nitrate containing drugs like nitroglycerine and sodium nitroprusside 6.…”

Section: Discussionmentioning

confidence: 99%

Benzocaine-induced methaemoglobinaemia: a life-threatening complication after a transoesophageal echocardiogram (TEE)

et al. 2013

View full text Add to dashboard Cite

Acquired methaemoglobinaemia is a potentially fatal impairment in oxygen delivery if not recognised early and treated appropriately. Benzocaine used as an anaesthetic for endoscopic procedures is an uncommon but clinically important precipitant of acquired methaemoglobinaemia. We present a case of an elderly woman who developed perioral cyanosis and desaturation 20 min after a transoesophageal echocardiogram. Further evaluation led to the diagnosis of benzocaine-induced methaemoglobinaemia and timely treatment with intravenous methylene blue was initiated.

show abstract

Section: Discussionmentioning

confidence: 99%

Benzocaine-induced methaemoglobinaemia: a life-threatening complication after a transoesophageal echocardiogram (TEE)

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Methemoglobinemia secondary to local anesthetic has been reported as a TEE-related complication resulting in hypoxemia. 19 …”

Section: Unexplained Hypoxemiamentioning

confidence: 99%

Transesophageal Echocardiography for the Noncardiac Surgical Patient

Rebel

Klimkina

Hassan

2012

International Surgery

View full text Add to dashboard Cite

Transesophageal echocardiography (TEE) has been established as a very valuable asset for patient monitoring during cardiac surgery. The value of perioperative TEE for patients undergoing noncardiac surgery is less clear. This article reviews the technical aspects of TEE and comments on the potential benefit of using TEE as a monitoring modality apart from cardiac surgery. Based on patient's comorbidities and/or injury pattern, TEE is a fast and minimally invasive approach to obtain important hemodynamic information, especially useful in a hemodynamically unstable patient. However, certain requirements for the use of the technique are necessary, most important the development of sufficient echocardiographic skills by the anesthesiologists. Indications, skill requirements, and possible complications of the technique are reviewed.

show abstract

“…Outros sistemas também auxiliam na manutenção da MetHb em níveis basais, destacando-se, entre eles, o ácido ascórbico, o glutation e NADPH desidrogenase. O glutation reduz muitas substân-cias oxidantes no sangue antes que elas ataquem a Hb 14 . Entretanto, em condições normais essas vias são menos significativas, tornando-se importantes somente quando a NADH-MR está comprometida 9 .…”

Section: Etiopatogeniaunclassified

“…Os agentes oxidantes aceleram a oxidação da Hb de 100 a 1.000 vezes e acabam sobrepujando a capacidade dos sistemas redutores endó-genos 17 . O contato com essas substâncias ocorre pelo tratamento com inúmeros fármacos 1,5,7,11,14,[18][19][20][21][22][23] , intoxicação por pesticidas, herbicidas, fertilizantes 3 , fumaça de escapamento de automóveis 13 e substâncias químicas industriais 24,25 . Entre os fármacos mais implicados, destacam-se os anestésicos locais (benzocaína, lidocaína e prilocaína), a dapsona, os derivados da fenacetina e os antimaláricos 16 .…”

Section: Classificaçãounclassified

“…Other systems also help to maintain a low level of MetHb; among them, ascorbic acid, gluthation, and NADPH dehydrogenase should be mentioned. Gluthation reduces several oxidizing substances in the blood before they attack the Hb 14 . However, under normal conditions those pathways are less significant, but become important when NADH-MR is disrupted 9 .…”

Section: Etiopathogenymentioning

confidence: 99%

See 1 more Smart Citation

Metemoglobinemia: do diagnóstico ao tratamento

Nascimento¹,

Pereira²,

Mello³

et al. 2008

Rev. Bras. Anestesiol.

121

View full text Add to dashboard Cite

Rev Bras AnestesiolARTIGO DIVERSO 2008; 58: 6: 651-664 MISCELLANEOUS RESUMO Nascimento TS, Pereira ROL, Mello HLD, Costa J -Metemoglobinemia: do Diagnóstico ao Tratamento. JUSTIFICATIVAS E OBJETIVOS: CONCLUSÃO:A metemoglobinemia é condição potencialmente grave, cujo diagnóstico depende do alto grau de suspeição. Em geral, os anestesiologistas, no período perioperatório, são os primeiros a detectarem o problema e devem liderar a condução do tratamento.

show abstract

Methemoglobinemia after transesophageal echocardiography: a life-threatening complication

Cited by 14 publications

References 7 publications

Benzocaine-induced methaemoglobinaemia: a life-threatening complication after a transoesophageal echocardiogram (TEE)

Benzocaine-induced methaemoglobinaemia: a life-threatening complication after a transoesophageal echocardiogram (TEE)

Transesophageal Echocardiography for the Noncardiac Surgical Patient

Metemoglobinemia: do diagnóstico ao tratamento

Contact Info

Product

Resources

About