Methemoglobinemia in a Newborn

Shakya, Shristi; Shrestha, Nisha Jyoti; Subedi, Kalpana

doi:10.3126/mjsbh.v19i1.26567

Cited by 1 publication

(1 citation statement)

References 5 publications

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“…Due to its anti-inflammatory, antioxidant, neuroprotective, and antiparasitic properties [4][5][6][7][8] MB has been considered a multifunctional drug with uses at preventive [4,6], curative [9], and postoperative [10][11][12] care. The main clinical indications of MB are for the treatment of malaria [8,[11][12][13] and methemoglobinemia [14].…”

Section: Introductionmentioning

confidence: 99%

Methylene Blue for the Treatment of Health Conditions: a Scoping Review

Galvan

Borsoi

Julek

et al. 2021

Braz. arch. biol. technol.

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studies evaluating effective drugs for health conditions are of crucial importance for public health. Methylene blue (MB) is an accessible synthetic drug that presents low toxicity and has been used in several health areas due to its effectiveness. Objective: this scoping review aims to provide a comprehensive overview of relevant research regarding the use of MB for the treatment of health conditions. Methods: a fivestage framework Arksey and O'maley scoping review was conducted. The literature was searched in Cochrane Library database using Mesh term "methylene blue". Data were collected by two independent reviewers and submitted to descriptive synthesis. Results: The search resulted in 429 records, from which 16 were included after exclusion criteria were applied. The therapeutic use of MB was identified for acute conditions (malaria and septic shock), chronic conditions (discogenic back pain, bipolar disorder, refractory neuropathic pain, and post-traumatic stress disorder), and postoperative care (vasoplegic syndrome, and pain after haemorrhoidectomy, lumbar discectomy, and traumatic thoracolumbar fixation). Conclusion: there is much evidence emerging from clinical trials about the therapeutic use of MB for acute, chronic, and HIGHLIGHTS  This scoping review summarizes the findings of clinical trials using methylene blue (MB) for the treatment of various health conditions.  This research method allowed mapping main findings, clarifying research topics, and identifying gaps in the literature.

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