Methicillin resistance of airborne coagulase-negative staphylococci in homes of persons having contact with a hospital environment

Lis, Danuta O.; Pacha, J.; Idzik, Danuta

doi:10.1016/j.ajic.2008.09.013

Cited by 33 publications

(16 citation statements)

References 25 publications

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“…The presence of antibiotic resistant bacteria or resistance determinants has been reported sporadically for more than 20 years in different countries (Faria et al 2009;Resch et al 2008;Ruscher et al 2009;Lis et al 2009;Seyler et al 2004). CNS were the most Fig.…”

Section: Discussionmentioning

confidence: 95%

“…These are traditionally grouped into coagulase positive (CPS) and coagulase-negative Staphylococci (CNS) (Resch et al 2008). Main habitats of these bacteria are skin, skin glands and mucous membranes of humans and animals (Sudagidan et al 2005;Lis et al 2009;Koksal et al 2007). CNS have become the most frequently isolated organisms from bovine intra mammary infections in several countries and their prevalence is generally highest at calving (Katsuda et al 2005;Schultz et al 2009).…”

Section: Introductionmentioning

confidence: 99%

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Identification and characterization of a Streptomyces sp. isolate exhibiting activity against multidrug-resistant coagulase-negative Staphylococci

et al. 2011

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The resistance of 220 coagulase-negative Staphylococci (CNS) (associated with animal disease) to 13 antibiotics were determined using the disk diffusion method. 35.9% of multidrug-resistant coagulase-negative Staphylococci (MR-CNS) exhibited resistance to five or more than five antibiotics; all of these bacteria were resistant to methicillin too. The new Streptomyces sp. ABRIINW111 was isolated from the Zagros Mountains Hamadan, Iran. The 16S rDNA sequence of the isolate indicated that it has 98% similarity to S. levis, but some mutations in the alpha and gamma regions of the 16S rDNA sequence emphasize the probability of the existence of a new species. Preliminary and secondary antibacterial screenings revealed that the isolate is active against gram negative and positive bacteria. The diethyl ether extracted metabolite of the Streptomyces sp. ABRIINW111 showed an effective antibacterial activity against MR-CNS. So the diethyl ether extract of the new Streptomyces sp. strain ABRIINW111 can inhibit the MR-CNS in vitro, and it can offer a new approach to treat MR-CNS infectious patients.

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Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

Identification and characterization of a Streptomyces sp. isolate exhibiting activity against multidrug-resistant coagulase-negative Staphylococci

et al. 2011

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“…These infections can also affect medical personnel, patient’s visitors and hospital support staff [2]. Approximately 60%–70% of nosocomial infections are associated with the use various types of medical-devices with surfaces contaminated with pathogenic bacteria [3] and what is more, the contaminated hands of medical personnel are also considered as one of the pathways of nosocomial infection spread.…”

Section: Introductionmentioning

confidence: 99%

Biofilm Formation and Antimicrobial Susceptibility of Staphylococcus epidermidis Strains from a Hospital Environment

Wojtyczka

Orlewska

Kępa

et al. 2014

IJERPH

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The hospital environment microflora comprise a wide variety of microorganisms which are more or less pathogenic and where staphylococci are one of the most common types. The aim of the presented study was to evaluate the prevalence of the biofilm forming coagulase-negative staphylococci (CoNS) in a hospital environment as a risk factor for nosocomial infections. Among 122 isolated and tested strains of CoNS the most frequent were: S. epidermidis—32 strains, S. haemolyticus—31 strains, S. capitis subsp. capitis—21 strains, S. hominis—11 strains, S. cohnii subsp. cohnii—nine strains. In case of CoNS, the main molecule responsible for intercellular adhesion is a polysaccharide intercellular adhesin (PIA), encoded on the ica gene operon. The analysis revealed the presence of the icaADBC operon genes in 46.88% of S. epidermidis isolates. IcaA and icaD were present in 34.38% and 28.13% of strains respectively while IcaC gene was present in 37.50% of strains. IcaB gene was found in 21.88% of S. epidermidis strains. In 15 (63%) strains all icaADBC operon genes were observed. The assessment of antibacterial drugs susceptibility demonstrated that analyzed CoNS strains were highly resistant to macrolides and lincosamides and more sensitive to rifampicin and linezolid. Our data indicates that the hospital environment can be colonized by biofilm forming coagulase-negative staphylococci and transmission of these strains can cause an increased risk of serious nosocomial infections.

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“…More importantly, most of these species are resistant to methicillin, which also refers to the fact that they are resistant to other beta-lactam antibiotics at the same time. It is also known that methicillin resistance in CoNS plays a role in transferring to other CoNS (Szewczyk et al 2003, Szewczyk et al 2004, Lis et al 2009, Bagcigil et al 2012. Due to the known importance of staphylococci and methicillin resistance in public health, apart from studying culturable airborne bacteria, investigations of methicillin resistant S. aureus MRSA were also targeted during this study.…”

Section: Discussionmentioning

confidence: 99%

Culturable airborne bacteria and isolation of methicillin-resistant coagulase-negative staphylococci from outdoor environments on European side of Istanbul, Turkey

Sivri

Bağcıgil

Metiner

et al. 2016

Archives of Environmental Protection

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This study is aimed to investigate culturable airborne bacteria concentrations and the composition of methicillin-resistant staphylococci in eleven different locations on the basis of specifi c activities conducted within different parts of the European side of Istanbul. The highest bacterial levels were observed at the Bakirkoy station (1 100 CFU/m 3 ) while the second highest levels were found at the Bahcelievler station (1 040 CFU/m 3 ) in October; the lowest levels (10 CFU/m 3 ) were measured at other different stations (Atakoy, Yesilkoy). Fifteen methicillin--resistant isolates [Staphylococcus hominis (n=11), S. cohnii spp. cohnii (n=2), S. sciuri (n=1), S. capitis spp. capitis (n=1)] were identifi ed. The disc diffusion method was used to identify the antimicrobial resistance of these isolates, it was observed that the most common resistance was to penicillin (P) (n=11), doxycycline (DO) (n=4) and tetracycline (T) (n=5). None of the isolates was resistant to imipenem, amoxicillin/clavulanic acid, vancomycin (IPM, AMC, VA). However, multiple antimicrobial resistance was found to be 26.7%. The results of this study revealed the importance of isolated methicillin-resistant staphylococci in the stations with densely active human population and traffi c, for public health. As a result, the importance of resting along known shorelines, where culturable airborne bacteria concentrations are much lower, and its importance for human health have been emphasized.

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Methicillin resistance of airborne coagulase-negative staphylococci in homes of persons having contact with a hospital environment

Cited by 33 publications

References 25 publications

Identification and characterization of a Streptomyces sp. isolate exhibiting activity against multidrug-resistant coagulase-negative Staphylococci

Identification and characterization of a Streptomyces sp. isolate exhibiting activity against multidrug-resistant coagulase-negative Staphylococci

Biofilm Formation and Antimicrobial Susceptibility of Staphylococcus epidermidis Strains from a Hospital Environment

Culturable airborne bacteria and isolation of methicillin-resistant coagulase-negative staphylococci from outdoor environments on European side of Istanbul, Turkey

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