Methicillin‐resistant and methicillin‐sensitive Staphylococcus aureus laryngitis

Abstract

This is the largest, single, case series of patients with MRSA laryngitis. Our study findings suggest that the diagnosis may be more common than previously recognized, and that the presenting signs and symptoms may be subtle and similar to MSSA. Diagnosis can be made via in-office laryngeal culture. Clinicians must have a high index of suspicion for this diagnosis.

Factors Associated With Infectious Laryngitis: A Retrospective Review of 15 Cases

“…This study along with previously published reports 9–11 demonstrates that a 14-day course of antibiotics may not be sufficient to treat chronic bacterial laryngitis. In our cohort, the shortest duration of antibiotics that was effective was 3 weeks for Pseudomonas aeruginosa laryngitis.…”

“…11 These patients were dysphonic (vocal roughness, fatigue, and decreased vocal endurance) and had thickened vocal folds, edema, crusting, and debris on exam. 11 All 6 patients were diagnosed via in-office cultures and were treated with multiple courses (2–4 weeks) of trimethoprim-sulfamethoxazole. 11 Additionally, there are a few case reports describing patients with prolonged dysphonia, culture proven MRSA laryngitis, and treatment with extended courses of trimethoprim-sulfamethoxazole.…”

“…11 All 6 patients were diagnosed via in-office cultures and were treated with multiple courses (2–4 weeks) of trimethoprim-sulfamethoxazole. 11 Additionally, there are a few case reports describing patients with prolonged dysphonia, culture proven MRSA laryngitis, and treatment with extended courses of trimethoprim-sulfamethoxazole. 9,10 …”

MRSA chronic bacterial laryngitis: A growing problem

“…) . Treatment usually requires extended targeted antibiotic therapy . Like all open‐ended passageways in the body, the larynx has been shown to have normal colonization with bacteria.…”

“…Methicillin‐resistant staphylococcus aureus (MRSA) has been increasingly identified as a pathogen responsible for chronic bacterial laryngitis . MRSA chronic laryngitis is difficult to distinguish from non‐MRSA chronic bacterial laryngitis on physical examination (Fig. ).…”