Methicillin-resistant Staphylococcus aureus in the western region of Saudi Arabia: prevalence and antibiotic susceptibility pattern

Abstract

BACKGROUND AND OBJECTIVESMethicillin-resistant Staphylococcus aureus (MRSA) emerged in 1960 and was a problem confined largely to the healthcare setting, or hospital-associated MRSA (HA-MRSA). In the 1990s, community-associated MRSA (CA-MRSA) infections appeared. In Saudi Arabia, the prevalence of MRSA has increased in the past ten years and severe community-acquired infection has been reported. Our objective was to investigate the prevalence of MRSA and their antibiotic susceptibilities in the western region of Saudi Arabia.DESIGN AND SETTINGA retrospective review of the medical records of 186 S aureus infected patients diagnosed from November 2009 through October 2010.METHODSS aureus was Identified based on Gram stain, catalase and coagulase tests. Susceptibility testing was performed using antibiotic discs and the VITEK 2 system.RESULTSMRSA was isolated in 39.5% of the specimens. The isolates were commonly associated with wound, skin, and soft tissue infections (87.3%). The prevalence of MRSA was highest among patients who were 56 years old or older (52.2%). CA-MRSA infections represented 31.5% of community S aureus infections, while HA-MRSA accounted 52.6% of hospital S aureus (P=.0029). All MRSA isolates in our study were susceptible to vancomycin, linozolid and teicoplanin. However, multi-resistance was observed in 29.1% of the isolates and was significantly higher among HA-MRSA (P=.03).CONCLUSIONSThe prevalence of MRSA was 39.5%, and infection was commonly associated with wound, skin, and soft tissue infections. MRSA was more prevalent in hospitals and among older patients. All MRSA susceptible to vancomycin, linozolid and teicoplanin.

Antimicrobial susceptibility pattern of Gram negative bacteria isolated from intensive care units in Al-Ahsa, Kingdom of Saudi Arabia

“…However, their study comprises both Saudi and non-Saudi nationals while the ICU isolates in the present study were from Saudi nationals only as there were no available data for non-Saudis in this region at the time of the study. Also, similar to the report in the present investigation are those from a previous report (El-Amin and Faidah, 2012) in which there was a higher number of ICU males than females. This therefore indicates that there would be variations in different hospitals, within a country as well as around different regions of the world.…”

Bacterial isolates exhibiting multidrug resistance, hemolytic activity, and high 16S rRNA gene similarity with well‐known pathogens found in camel milk samples of Riyadh region

“…Distribution of multidrug‐resistant Staphylococcus aureus and/or MRSA in the Kingdom is widely reported, and the incidence of a different type of MRSA was found to be especially higher in the Riyadh region . These previously published studies and the study presented here strongly suggest that camel milk serves as an important reservoir and carrier of such pathogens.…”

Prevalence of Methicillin Resistance Staphylococcus Aureus (MRSA) Infection and Incidence Rate of Diabetic MRSA Patients in Northern Region of KSA

“…Other study demonstrated Most isolates were from wound sites (71%) however in our case most isolate were from eye infection [10] another similar study shows MRSA was isolated in 39.5% of the specimens. The prevalence of MRSA was highest among patients who were 56 years old or older (52.2%) [11]. As compare to our study in which the young patients were more susceptible.…”