Methicillin-resistant<i>Staphylococcus aureus</i>, Western Australia

Dailey, Lynne; Coombs, Geoffrey W.; O’Brien, Frances; Pearman, J.W.; Christiansen, Keryn; Grubb, W.B.; Riley, Thomas V.

doi:10.3201/eid1110.050125

Cited by 41 publications

(35 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most strains of HA-MRSA fall into five broad lineages that are responsible for the majority of infections worldwide (38). Infections due to CA-MRSA can be seen in hospital settings, with occasional major outbreaks (4,7), while HA-MRSA strains are also able to circulate within communities (32).…”

mentioning

confidence: 99%

Use of a Single-Nucleotide Polymorphism Genotyping System To Demonstrate the Unique Epidemiology of Methicillin-Resistant Staphylococcus aureus in Remote Aboriginal Communities

et al. 2006

View full text Add to dashboard Cite

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as a major public health problem in Australia, as in many other parts of the world. High rates of CA-MRSA skin and soft tissue infection have been reported from Aboriginal communities. We used a single-nucleotide polymorphism (SNP) genotyping typing system based on the multilocus sequence type (MLST) database to investigate the epidemiology of CA-MRSA and methicillin-sensitive S. aureus (MSSA) over a 12-month period in three remote Aboriginal communities of Northern Australia. This was supplemented by real-time PCR for Panton-Valentine leukocidin (PVL) genes, staphylococcal cassette chromosome mec (SCCmec) typing, and antimicrobial susceptibility testing. S. aureus was recovered from pyoderma lesions on 221 occasions and throat swabs on 44 occasions. The median monthly recovery rate of S. aureus from skin sores was 58% (interquartile range, 62 to 78%), and there was no seasonal variation. Twenty-three percent of isolates were CA-MRSA; the proportion was similar across the communities and did not vary over the study period. Erythromycin resistance was found in 47% of CA-MRSA and 21% of MSSA. SNP-based typing identified 14 different clonal complexes (cc); however, cc75 was predominant, accounting for 71% of CA-MRSA isolates. These were confirmed as ST75-like by using an additional SNP and MLST of selected isolates. All but one of the cc75 isolates had SSCmec type IV (one had type V), and all were PVL negative. Monthly tracking of SNP-based cc types showed a highly dynamic process. ST75-MRSA-IV appears to be unique to the region and probably evolved de novo in remote Aboriginal communities.

show abstract

mentioning

confidence: 99%

Use of a Single-Nucleotide Polymorphism Genotyping System To Demonstrate the Unique Epidemiology of Methicillin-Resistant Staphylococcus aureus in Remote Aboriginal Communities

et al. 2006

View full text Add to dashboard Cite

show abstract

“…One disadvantage of attempted decolonization is the development of resistance to the agents used. Mupirocin resistance has been documented in several studies (131)(132)(133)(134), usually associated with prolonged use or repeated courses of mupirocin. In Canada, Mulvey et al (109) have reported mupirocin resistance rates of up to 50% in community isolates on the prairies.…”

Section: Decolonizationmentioning

confidence: 99%

“…In Canada, Mulvey et al (109) have reported mupirocin resistance rates of up to 50% in community isolates on the prairies. Limiting its use to a maximum course of five to 10 days and ensuring a minimum time period of one month between recurrent use are strategies that have been found to be effective in preventing the emergence of mupirocin resistance (133,134).…”

Section: Decolonizationmentioning

confidence: 99%

See 1 more Smart Citation

Le Staphylococcus aureus méthicillinorésistant d’origine non nosocomiale dans les communautés autochtones du Canada

Irvine¹,

pédiatrie²

2012

Paediatrics &Amp; Child Health

View full text Add to dashboard Cite

“…[64][65][66] Similar low rates in western Australia have also been attributed to long-standing policies of rigorous screening and isolation. 67 The literature is contradictory about the benefit of masks in the prevention of cross-transmission of S. aureus, 49 apart from their role in preventing droplet transmission in the setting of a patient colonized with MRSA with respiratory symptoms. 68 Vancomycin-resistant enterococci does not colonize the respiratory tract, and there is no role for masks in preventing cross-transmission.…”

Section: Barrier Precautionsmentioning

confidence: 99%

Hospital infection control strategies for vancomycin-resistant Enterococcus, methicillin-resistant Staphylococcus aureus and Clostridium difficile

Johnston

Bryce²

2009

Canadian Medical Association Journal

View full text Add to dashboard Cite

Methicillin-resistantStaphylococcus aureus, Western Australia

Abstract: Endemic MRSA persists in Western Australia despite control measures.

Cited by 41 publications

References 27 publications

Use of a Single-Nucleotide Polymorphism Genotyping System To Demonstrate the Unique Epidemiology of Methicillin-Resistant Staphylococcus aureus in Remote Aboriginal Communities

Use of a Single-Nucleotide Polymorphism Genotyping System To Demonstrate the Unique Epidemiology of Methicillin-Resistant Staphylococcus aureus in Remote Aboriginal Communities

Le Staphylococcus aureus méthicillinorésistant d’origine non nosocomiale dans les communautés autochtones du Canada

Hospital infection control strategies for vancomycin-resistant Enterococcus, methicillin-resistant Staphylococcus aureus and Clostridium difficile

Contact Info

Product

Resources

About